ALERT-- adverse late effects of cancer treatment. Volume 1, General concepts and specific precepts /

ALERT-- adverse late effects of cancer treatment. Volume 1, General concepts and specific precepts /

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Bibliographic Details
Imprint:Berlin : Springer, 2014
Description:1 online resource (xxiv, 311 pages) : illustrations (some color).
Language:English
Series:Medical radiology
Medical radiology (Series)
Subject:
Cancer -- Treatment -- Complications.
Antineoplastic Agents -- adverse effects.
Radiotherapy -- adverse effects.
Cancer -- Treatment -- Complications.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11081026
Hidden Bibliographic Details
Varying Form of Title:General concepts and specific precepts
Other authors / contributors:Rubin, Philip, 1927- editor.
Constine, Louis S., editor.
Marks, Lawrence (Lawrence B.), editor.
ISBN:9783540723141
3540723145
9783540723134
Notes:Includes bibliographical references.
Print version record.
Summary:The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.
Other form:Print version: ALERT - adverse late effects of cancer treatment 9783540767039
Standard no.:10.1007/978-3-540-72314-1
Table of Contents:
  • Prologue: Surviving Cancer: SEER Statistics / Craig C. Earle, Lois B. Travis and Louis S. Constine
  • Biocontinuum of the Pathophysiology Paradigm / Philip Rubin and George Casarett
  • Biophysiopathology of the Microvasculature and Microcirculation / Philip Rubin and Luis Fajardo
  • Molecular Mechanisms of Radiation Induced Injury / Isabel L. Jackson, Phil Rubin, Caroline Hadley and Zeljko Vujaskovic
  • Biodetection and Biointervention: Cytokine Pathways as a Rationale for Anti-cytokine Interventions Post-Radiation / Paul R. Graves, Isabel Jackson, Mitchell S. Anscher, Ross Mikkelsen and Zeljko Vujaskovic
  • Quantitative/Objective Analyses of RT-Induced Late Normal Tissue Injury Using Functional Imaging / Jiho Nam, Mike E. Robbins and Lawrence B. Marks
  • Biograding of Normal Tissue TNM Toxicity Taxonomy: Scoring the Adverse Effects of Cancer Treatment / Andy M. Trotti and Philip Rubin
  • Understanding and Predicting Radiation-Associated Normal Tissue Injury: A Global and Historical Perspective / Michael T. Milano, Philip Rubin and Lawrence B. Marks
  • Biotoxicity of Chemotherapy / Chunkit Fung and Kishan J. Pandya
  • BioSurveillance and Longitudinal Lifelong Guidelines / Andrea K. Ng and Melissa M. Hudson
  • BioPediatric Complexities of Growth and Development / Arnold C. Paulino, Sughosh Dhakal and Louis S. Constine
  • BioGenetic and Host Implications / Barry S. Rosenstein
  • Bioengineering of Irradiated Normal Tissues by Bone Marrow Stem Cells / Joel S. Greenberger and Michael W. Epperly
  • Radiotherapy-Induced Carcinogenesis and Leukemogenesis: Mechanisms and Quantitative Modeling / David J. Brenner, Igor Shuryak and Rainer K. Sachs
  • The Bioepidemiology of Multiple Primary Cancers / Lois B. Travis and Andrea K. Ng
  • Radiation-Related Second Primary Cancers: Clinical Perspectives / David C. Hodgson, Andrea Ng and Lois B. Travis
  • The Psychosocial and Functional Impact of Radiation Therapy / Jason Q. Purnell, Karen Mustian, Pascal Jean-Pierre, Oxana Palesh, Luke J. Peppone [and 3 others]
  • Nursing / Sheila Judge Santacroce and Madelyn Rubin
  • Economic Consequences of Late Effects / Andre Konski
  • Radiological and Nuclear Terrorism: Relevance to the Radiation Oncology and Biology Communities / C. Norman Coleman, Nathaniel Hafer, Bert Maidment, Ronald Manning, Pat Prasanna and Paul Okunieff.
  • BioContinuum of Effects of Multimodal Therapy
  • BioMolecular Mechanisms and Pathways of Normal Tissue Damage
  • BioPathology of Radiation and Chemotherapy
  • BioImaging of the Longitudinal Normal Tissue Injury
  • BioScoring Systems for Acute and Late Effects
  • BioPediatric Complexities of Growth and Development
  • Bioepidemiology
  • BioGenetic and Host Implications
  • Radiotherapy-Induced Biocarcinogenesis and Leukemogenesis
  • BioManagement and BioPrevention.-BioSurveillance and Longitudinal Lifelong Guidelines
  • Specific Precept: Medical Legal Issues: Malpractice Issues
  • Insurance, Economics: Cost of Care
  • Nursing
  • Psychologic Issues
  • Social Worker Issues: Quality of Life and Activities of Daily Living.

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