Challenges and opportunities for respiratory syncytial virus vaccines /

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Bibliographic Details
Imprint:	Berlin : Springer-Verlag, 2013.
Description:	1 online resource (xi, 409 pages) : illustrations.
Language:	English
Series:	Current topics in microbiology and immunology ; volume 372 Current topics in microbiology and immunology ; 372.
Subject:	Vaccines. Medicine. Emerging infectious diseases. Emerging infectious diseases. Medicine. Vaccines. Respiratory Syncytial Virus Infections -- etiology. Respiratory Syncytial Virus Infections -- immunology. Respiratory Syncytial Virus Infections -- therapy. Respiratory Syncytial Virus Vaccines -- therapeutic use.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11083497

Hidden Bibliographic Details
Other authors / contributors:	Anderson, Larry J., editor. Graham, Barney S., editor.
ISBN:	9783642389191 3642389198 364238918X 9783642389184 9783642389184
Notes:	Includes bibliographical references and index. Print version record.
Summary:	Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure. The success of RSV immune prophylaxis and the availability of ever more powerful tools to study the immune response and pathogenesis of disease, combined with the ability to construct a wide variety of vaccines using different vaccine platforms, give us grounds to believe that an RSV vaccine is within reach. This book brings together in one source what is currently known about the virus: its clinical and epidemiologic features; the host response and pathogenesis of the disease; vaccines, vaccine platforms, and treatment; and animal and tissue culture models of RSV infection. It is designed to organize the critical information relevant to RSV vaccine development, facilitate the assimilation of data, and speed progress toward producing a safe and effective vaccine.
Other form:	Print version: Challenges and opportunities for respiratory syncytial virus vaccines 364238918X

Table of Contents:

Virology, Pathogenesis, and Clinical and Epidemiological Features of Disease. Respiratory Syncytial Virus: Virology, Reverse Genetics, and Pathogenesis of Disease / Peter L. Collins, Rachel Fearns, Barney S. Graham
Clinical and Epidemiologic Features of Respiratory Syncytial Virus / Caroline B. Hall, Eric A.F. Simőes, Larry J. Anderson
Influence of Respiratory Syncytial Virus Strain Differences on Pathogenesis and Immunity / José A. Melero, Martin L. Moore
Structure and Function of Respiratory Syncytial Virus Surface Glycoproteins / Jason S. McLellan, William C. Ray, Mark E. Peeples
Respiratory Syncytial Virus and Reactive Airway Disease / Matthew T. Lotz, Martin L. Moore, R. Stokes Peebles Jr.
Host Response to Infection and Genetics of Disease. Human Genetics and Respiratory Syncytial Virus Disease: Current Findings and Future Approaches / Eun Hwa Choi, Hoan Jong Lee, Stephen J. Chanock
Innate Immune Responses to Respiratory Syncytial Virus Infection / Sumanta Mukherjee, Nicholas W. Lukacs
The Adaptive Immune Response to Respiratory Syncytial Virus / Steven M. Varga, Thomas J. Braciale
Respiratory Syncytial Virus Mechanisms to Interfere with Type 1 Interferons / Sailen Barik
Host Gene Expression and Respiratory Syncytial Virus Infection / Ralph A. Tripp, Asuncion Mejias, Octavio Ramilo
Consequences of Immature and Senescent Immune Responses for Infection with Respiratory Syncytial Virus / Allison M.W. Malloy, Ann R. Falsey, Tracy J. Ruckwardt
Vaccine Platforms and Treatment Options. Respiratory Syncytial Virus Disease: Prevention and Treatment / Helen Y. Chu, Janet A. Englund
Live-Attenuated Respiratory Syncytial Virus Vaccines / Ruth A. Karron, Ursula J. Buchholz, Peter L. Collins
Subunit and Virus-Like Particle Vaccine Approaches for Respiratory Syncytial Virus / Trudy G. Morrison, Edward E. Walsh
Gene-Based Vaccine Approaches for Respiratory Syncytial Virus / Rebecca J. Loomis, Philip R. Johnson
Animal and Tissue Culture Models of Infection. Bovine Model of Respiratory Syncytial Virus Infection / Geraldine Taylor
The Cotton Rat Sigmodon Hispidus Model of Respiratory Syncytial Virus Infection / Marina S. Boukhvalova, Jorge C.G. Blanco
The Mouse Model of Respiratory Syncytial Virus Disease / Peter J. Openshaw
Human Airway Epithelial Cell Cultures for Modeling Respiratory Syncytial Virus Infection / Raymond J. Pickles
Conclusions. Challenges and Opportunities for Respiratory Syncytial Virus Vaccines / Barney S. Graham, Larry J. Anderson.

Challenges and opportunities for respiratory syncytial virus vaccines /

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