Cardiovascular imaging : arterial and aortic valve inflammation and calcification /

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Bibliographic Details
Imprint:Cham : Springer, [2014]
©2015
Description:1 online resource (xiv, 389 pages) : illustrations (some color)
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11089286
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Other authors / contributors:Aikawa, Elena, editor.
ISBN:9783319092683
3319092685
9783319092676
3319092677
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (SpringerLink, viewed December 4, 2014).
Summary:This book provides comprehensive reviews on our most recent understanding of the molecular and cellular mechanisms underlying atherosclerosis and calcific aortic valve disease (CAVD) as visualized in animal models and patients using optical molecular imaging, PET-CT, ultrasound and MRI. In addition to presenting up-to-date information on the multimodality imaging of specific pro-inflammatory or pro-calcification pathways in atherosclerosis and CAVD, the book addresses the intriguing issue of whether cardiovascular calcification is an inflammatory disease, as has been recently supported by seve.
Other form:Print version: Aikawa, Elena Cardiovascular Imaging : Arterial and Aortic Valve Inflammation and Calcification Cham : Springer International Publishing,c2014 9783319092676
Standard no.:10.1007/978-3-319-09268-3
Table of Contents:
  • Foreword; References; Preface; Contents; Part I: Preclinical Imaging of Mechanisms of Atherosclerosis and Its Complications; 1: Pathobiology and Mechanisms of Atherosclerosis; 1.1 Introduction; 1.2 Plaque Formation; 1.3 Plaque Progression; 1.4 Plaque Complications; 1.4.1 Plaque Rupture; 1.4.2 Plaque Erosion; 1.4.3 Intraplaque Hemorrhage (IPH); 1.5 Atherosclerosis Imaging; 1.6 Anatomic Atherosclerotic Plaque Imaging; 1.6.1 X-Ray Computed Tomography; 1.6.2 Magnetic Resonance Imaging; 1.6.3 Angiography; 1.6.4 Angioscopy; 1.6.5 Intravascular Ultrasound; 1.6.6 Optical Coherence Tomography
  • 1.7 Functional Atherosclerotic Plaque Imaging1.7.1 Cell Activation Imaging; 1.7.2 Phagocytosis Imaging; 1.7.3 Imaging of Lipid Uptake/Foam Cell Formation; 1.7.4 Imaging Metabolic Activity; 1.7.5 Apoptosis Imaging; 1.7.6 Oxidative Stress Imaging; 1.7.7 Angiogenesis Imaging; 1.7.8 Proteinase Imaging; 1.7.9 Imaging Thrombosis; 1.7.10 Imaging Calcification; Conclusion; References; 2: Ultrasound Molecular Imaging of Endothelial Cell Activation and Damage in Atherosclerosis; 2.1 B-Mode Ultrasound Imaging of Atherosclerosis; 2.1.1 Focused Review of Ultrasound Physics
  • 2.1.2 Ultrasound of Imaging of Plaque Burden2.1.3 Imaging Plaque Composition; 2.1.4 Mechanical Properties; 2.1.5 Vasa Vasorum and Plaque Neovessel Imaging; 2.2 Ultrasound Molecular Imaging of Atherosclerosis; 2.2.1 Basics of Ultrasound Molecular Imaging; 2.2.1.1 Ultrasound Contrast Agents; 2.2.1.2 Targeted Microbubble Contrast Agents; 2.2.1.3 Targeted Contrast-Enhanced Ultrasound Molecular Imaging; 2.2.2 Molecular Targets of Atherosclerosis Accessible to Ultrasound Contrast Agents; 2.2.3 Ultrasound Molecular Imaging of Atherosclerosis; 2.2.3.1 Non-ligand Microbubble Targeting
  • 2.2.3.2 Endothelial Cell Adhesion MoleculesP-Selectin; ICAM-1 and VCAM-1; Platelets and Thrombus; 2.3 Summary; References; 3: Molecular Imaging of Macrophages in Atherosclerosis; 3.1 Conventional Imaging Modalities for Atherosclerotic Vascular Diseases; 3.2 Macrophages in Atherosclerotic Diseases; 3.3 Molecular Imaging; 3.4 Macrophage Imaging by Iron-Based Nanomaterials; 3.5 Macrophage Imaging by Nuclear Medicine; 3.6 Imaging of Macrophage-Derived Proteases in Atherosclerotic Plaques; 3.7 Imaging of Plaque Macrophages by HDL-Based Probes
  • 3.8 Macrophage Imaging in Other Cardiovascular Diseases3.9 Macrophage Imaging in Fat Tissue; 3.10 Future Perspectives; References; 4: Intravascular Molecular Imaging of Proteolytic Activity; 4.1 Background; 4.2 High-Risk Plaque Features; 4.2.1 Plaque Proteolytic Activity; 4.3 Coronary Artery Molecular Imaging; 4.3.1 Clinical Trials; 4.4 Intravascular NIRF Imaging; 4.4.1 Intravascular NIRF Imaging Platforms; 4.4.1.1 One-Dimensional In Vivo Intravascular NIRF Sensing; 4.4.1.2 Two-Dimensional In Vivo Intravascular NIRF Imaging; 4.4.1.3 In Vivo Intravascular NIRF-OFDI Molecular-Structural Imaging