Free radicals in ENT pathology /

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Bibliographic Details
Imprint:	Cham : Humana Press, [2015]
Description:	1 online resource : color illustrations.
Language:	English
Series:	Oxidative stress in applied basic research and clinical practice, 2197-7232 Oxidative stress in applied basic research and clinical practice.
Subject:	Otolaryngology. Free radicals (Chemistry) -- Pathophysiology. Free radicals (Chemistry) -- Pathophysiology. Otolaryngology.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11093570

Hidden Bibliographic Details
Other authors / contributors:	Miller, Josef M., editor. Le Prell, Colleen G., editor. Rybak, Leonard P., editor.
ISBN:	9783319134734 3319134736 3319134728 9783319134727 9783319134727
Digital file characteristics:	text file PDF
Notes:	Includes bibliographical references and index. Online resource; title from PDF title page (Ebsco, viewed May 5, 2015).
Summary:	This comprehensive volume examines the current state of free radical biology and its impact on otology, laryngology, and head and neck function. The chapters collectively highlight the interrelationship of basic and translational studies in each area, define the challenges to translation, and identify the existing basic issues that demand investigation as well as the opportunities for novel intervention to prevent and treat ENT pathology and impairment. In each chapter, or in some cases pairs of chapters, the author(s) have included or married issues of basic research with translational challenges and research, thus defining the pathway by which new basic insights may lead to interventions to prevent or treat impairment. The final chapter of this book reflects a meeting of all the contributors, culminating in a discussion and ℓ́ℓwhite paperℓ́ℓ that identifies the challenges to the field and defines the studies and collaborations that may lead to improved understanding of free radical biology in ENT and, subsequently, ℗ℓ new interventions to medically treat ENT pathology.
Other form:	Printed edition: 9783319134727
Standard no.:	10.1007/978-3-319-13473-4

Table of Contents:

1. Introduction
Section 1: Basic Science of Free Radical Biology in ENT
2. Free radicals and oxidative stress: Basic concepts and misconceptions
3. A Question of Balance: Free Radicals and Cochlear Homeostasis
4. Antioxidants and their effect on stress-induced pathology in the inner ear
Section 2: Epidemiology of Hearing Loss
5. Role of free radicals in hearing loss due to heavy metals
6. The role of nutrition in healthy hearing: human evidence
Section 3: Oxidative Stress and Noise-Induced Hearing Loss
7. Basic mechanisms underlying noise-induced hearing loss
8. Oxidative stress in noise-induced hearing loss
9. Strategies for evaluating antioxidant efficacy in clinical trials assessing prevention of noise-induced hearing loss
Section 4: Oxidative Stress and Drug-Induced Hearing Loss
10. Aminoglycoside-induced oxidative stress: pathways and protection
11. Hearing loss after cis-platin: oxidative stress pathways and potential for protection
12. Assessment of interventions to prevent drug-induced hearing loss (DIHL)
Section 5: Oxidative Stress and Age-Related Hearing Loss
13. Age-related hearing loss: biochemical pathways and molecular targets
14. Genetics and age-related hearing loss
15. Mechanisms of age-related hearing loss
16. Interventions to prevent age-related hearing loss
Section 6. Hereditary Hearing Loss
17. Genes and hearing loss: relationship to oxidative stress and free radical formation
18. Strategies for the treatment of hereditary hearing loss
Section 7: Cochlear Implants, Radiation, Trauma and Other Stress Factors
19. Loss of Residual Hearing Initiated by Cochlear Implantation: Role of Inflammation-Initiated Cell
20. Role of oxidative stress in sudden hearing loss and Meniere?s disease
Section 8: Head and Neck
21. Role of free radicals in head and neck pathology
22. Free radicals and sleep apnea
23. Free radicals in nasal and paranasal disease
24. Conclusion.

Free radicals in ENT pathology /

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