Advances in the understanding of biological sciences using next generation sequencing (NGS) approaches /

Advances in the understanding of biological sciences using next generation sequencing (NGS) approaches /

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Bibliographic Details
Imprint:	Cham : Springer, 2015.
Description:	1 online resource (xii, 241 pages) : color illustrations
Language:	English
Series:	Online access with purchase: Springer (t)
Subject:	Nucleotide sequence. Genetics -- Technique. Genetics -- Technique. Nucleotide sequence.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11095305

Hidden Bibliographic Details
Other authors / contributors:	Sablok, Gaurav, editor. Kumar, Sunil, editor. Ueno, Saneyoshi, editor. Kuo, Jimmy, editor. Varotto, Claudio, editor.
ISBN:	9783319171579 3319171577 3319171569 9783319171562 9783319171562
Digital file characteristics:	text file PDF
Notes:	Includes index. Online resource; title from PDF title page (EBSCO, viewed July 23, 2015).
Summary:	This work is a compiled catalogue of such findings, where several NGS technologies ranging from the genomics, transcriptomics, metagenomics, single cell genomics, QTL, patho-genomics and patho-transcriptomics have been applied to delineate the mystery of the associated mutations, biological pathway transitions, transcriptional fluxes and patterns of host associated or adaptations to certain climatic conditions. The aims and scope of this book focuses more on the biological underpinning to initiate the cross-talks across the traits acquired or lost during the course of evolution. The structured framework of the present volume provides the applicative point of view of the NGS technologies and demonstrates the conceptual way of linking the experimentation to the NGS technologies, to aid in researchers to place their biological hypothesis in a larger context.
Other form:	Printed edition: 9783319171562
Standard no.:	10.1007/978-3-319-17157-9

Description
Summary:	Provides a global view of the recent advances in the biological sciences and the adaption of the pathogen to the host plants revealed using NGS. Molecular Omic's is now a major driving force to learn the adaption genetics and a great challenge to the scientific community, which can be resolved through the application of the NGS technologies. The availability of complete genome sequences, the respective model species for dicot and monocot plant groups, presents a global opportunity to delineate the identification, function and the expression of the genes, to develop new tools for the identification of the new genes and pathway identification. Genome-wide research tools, resources and approaches such as data mining for structural similarities, gene expression profiling at the DNA and RNA level with rapid increase in available genome sequencing efforts, expressed sequence tags (ESTs), RNA-seq, gene expression profiling, induced deletion mutants and insertional mutants, and gene expression knock-down (gene silencing) studies with RNAi and microRNAs have become integral parts of plant molecular omic's. Molecular diversity and mutational approaches present the first line of approach to unravel the genetic and molecular basis for several traits, QTL related to disease resistance, which includes host approaches to combat the pathogens and to understand the adaptation of the pathogen to the plant host. Using NGS technologies, understanding of adaptation genetics towards stress tolerance has been correlated to the epigenetics. Naturally occurring allelic variations, genome shuffling and variations induced by chemical or radiation mutagenesis are also being used in functional genomics to elucidate the pathway for the pathogen and stress tolerance and is widely illustrated in demonstrating the identification of the genes responsible for tolerance in plants, bacterial and fungal species.
Item Description:	Includes index.
Physical Description:	1 online resource (xii, 241 pages) : color illustrations
ISBN:	9783319171579 3319171577 3319171569 9783319171562