MicroRNA : cancer from molecular biology to clinical pactice /
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| Imprint: | Cham ; New York : Springer International Publishing, [2015] ©2015 |
|---|---|
| Description: | 1 online resource (xi, 235 pages). |
| Language: | English |
| Series: | Advances in experimental medicine and biology ; Volume 889. 0065-2598 Advances in experimental medicine and biology ; Volume 889. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11097083 |
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| 245 | 0 | 0 | |a MicroRNA : |b cancer from molecular biology to clinical pactice / |c Gaetano Santulli, editor. |
| 264 | 1 | |a Cham ; |a New York : |b Springer International Publishing, |c [2015] | |
| 264 | 4 | |c ©2015 | |
| 300 | |a 1 online resource (xi, 235 pages). | ||
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| 490 | 1 | |a Advances in experimental medicine and biology ; |v Volume 889. |x 0065-2598 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed December 17, 2015). | |
| 505 | 0 | |a Foreword; Contents; Contributors; Chapter 1: microRNAs in the Malignant Transformation Process; Introduction; Colorectal Cancer; Pancreatic Cancer; Malignant Peripheral Nerve Sheath Tumor; Prostate Cancer; Conclusion; References; Chapter 2: microRNA and Chronic Lymphocytic Leukemia; Chronic Lymphocytic Leukemia Before miRNAs Revolution; What Are miRNAs?; microRNA Signature in Chronic Lymphocytic Leukemia; miRNA's Mechanism of Action in CLL; miRNAs in CLL Mouse Models; miRNAs as Diagnostic and Prognostic Factors for CLL; miRNAs and RNA-Inhibition Therapy in CLL; Conclusions. | |
| 505 | 8 | |a MicroRNA Deregulation in GISTMicroRNAs Associated with Clinical and Pathological Features in GIST; MicroRNAs Associated with Chromosomal and Genetic Alterations in GIST; MicroRNAs in Imatinib Resistance in GIST; Clinical Implications of microRNAs in GIST; Conclusion; References; Chapter 5: Insights into the Role of microRNAs in Pancreatic Cancer Pathogenesis: Potential for Diagnosis, Prognosis, and Therapy; Introduction; Pancreatic Cancer: A Major Clinical Problem; Deregulation of miRNAs in Pancreatic Cancer; Role of miRNAs in Pancreatic Cancer. | |
| 505 | 8 | |a MiRNAs in Pancreatic Cancer Initiation and Promotion miRNAs in Pancreatic Cancer Metastasis; miRNAs in Chemoresistance of Pancreatic Cancer; Opportunities for the Clinical Use of miRNAs in Pancreatic Cancer Management; miRNAs as Diagnostic Markers; miRNAs in Prognostic Assessment; miRNAs as Therapeutic Targets; Conclusion and Future Perspectives; References; Chapter 6: microRNAs and Colorectal Cancer; Introduction; MiRNAs and Their Relationship to the Hallmarks of Cancer; Regulation of Cell Proliferation and Evasion of Growth Suppressors; Evasion of Apoptosis. | |
| 505 | 8 | |a Regulating Immortalization or Senescence Induction of Angiogenesis; Migration Invasion and Metastasis; Promotion of Genomic Instability; Reprogramming of Energy Metabolism; Evasion of Immune System and Inflammation; Clinical Implications of miRNAs in Colorectal Cancer; MiRNAs as Diagnostics; Circulating miRNAs; Mucosal Colon Wash Fluid; Feces; microRNAs as Therapeutics; References; Chapter 7: microRNAs and Prostate Cancer; Introduction; Role of miRNA in the Epigenetic Reprogramming of Prostate Cancer Metastasis; Epigenetic Silencing by EZH2 Regulate miRNA. | |
| 520 | |a This volume thoroughly explores of the functional role of microRNAs in cancer. It not only expertly describes the molecular mechanisms underlying the malignant transformation process but also compiles cutting-edge research on microRNAs in several forms of cancer, including colorectal cancer, pancreatic cancer, leukemia/lymphoma, prostate cancer, lung cancer, ovarian cancer, and bone cancer. Distinguished experts, currently working in prestigious institutions, elegantly discuss these fundamental themes. The text, which opens with a foreword by the renowned Dr. Carlo M. Croce, is enhanced by abundant color photographs, schemes, diagrams, and tables that fully support and complement the content. microRNA: Cancer is an ideal companion to both microRNA: Basic Science and microRNA: Medical Evidence. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice. | ||
| 650 | 0 | |a Tumor markers. |0 http://id.loc.gov/authorities/subjects/sh85138551 | |
| 650 | 0 | |a Non-coding RNA |0 http://id.loc.gov/authorities/subjects/sh2006003525 | |
| 650 | 0 | |a Cancer |x Genetic aspects. |0 http://id.loc.gov/authorities/subjects/sh85019509 | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x General. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
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| 650 | 7 | |a Tumor markers. |2 fast |0 (OCoLC)fst01158752 | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Santulli, Gaetano, |e editor. |0 http://id.loc.gov/authorities/names/n2013061166 |1 http://viaf.org/viaf/307422161 | |
| 776 | 0 | 8 | |i Print version: |a Santulli, Gaetano. |t MicroRNA: Cancer. |d Cham : Springer International Publishing, ©2016 |z 9783319237299 |
| 830 | 0 | |a Advances in experimental medicine and biology ; |v Volume 889. |x 0065-2598 | |
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