MHC Volume 1 : a practical approach /

MHC Volume 1 : a practical approach /

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Bibliographic Details
Imprint:	Oxford ; New York : Oxford University Press, ©1997.
Description:	1 online resource.
Language:	English
Series:	Practical approach series ; 180 Practical approach series ; 180.
Subject:	Major histocompatibility complex -- Laboratory manuals. Antigen Presentation. Major Histocompatibility Complex. Antigen-Presenting Cells. Proteins -- chemistry. Major histocompatibility complex. Laboratory manuals.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11127809

Hidden Bibliographic Details
Varying Form of Title:	Title on series title page: MHC 1
Other authors / contributors:	Fernandez, Nelson, Dr. Butcher, G. (Geoffrey W.)
ISBN:	0585483809 9780585483801 9780191565526 0191565520 0199635544 9780199635542 0199635536 9780199635535
Notes:	Includes bibliographical references and indexes.
Summary:	The major histocompatibility complex is the subject of much research in the immunology area. There is great interest in the structure of MHC proteins and in their function as antigen presenting molecules. Many immunology labs are now faced with the prospect of tackling biochemical and genetic techniques in order to study these molecules, and these two Practical Approach volumes provide the ideal introduction. MHC 1, Antigen Processing and Presentation, iscomplemented by MHC 2, Genes, Cells, and Molecules.
Other form:	Print version: MHC volume 1. Oxford ; New York : IRL Press at Oxford University Press, ; 1997 9780199635542

Description
Summary:	The major histocompatibility complex is the subject of much research in the immunology field. There is a great deal of interest in MHC proteins and their function as antigen presenting molecules, and many immunology laboratories are investigating biochemical and genetic techniques to study these molecules. The identification of peptide transporter genes and the elution of peptides from MHC molecules illustrate how rapidly our understanding of the MHC locus has advanced. This volume brings together the technologies which make these advances possible. It explains in detail the process such as peptide translocation into the ER, the application of mass spectrometry to the analysis of peptides bound to MHC, and signal detection via MHC class II molecules, which lead to either activation or cell death. The book is a comprehensive and thorough guide to the field of MHC research that graduates, post doctoral researchers, and academic staff and clinicians will find invaluable.
Physical Description:	1 online resource.
Bibliography:	Includes bibliographical references and indexes.
ISBN:	0585483809 9780585483801 9780191565526 0191565520 0199635544 9780199635542 0199635536 9780199635535