Autoimmunity : methods and protocols /

Autoimmunity : methods and protocols /

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Bibliographic Details
Edition:2nd ed.
Imprint:New York : Humana Press : Springer, ©2012.
Description:1 online resource (xiv, 504 pages) : illustrations (some color)
Language:English
Series:Methods in molecular biology, 1940-6029 ; 900
Methods in molecular biology (Clifton, N.J.) ; v. 900.
Subject:
Autoimmune diseases -- Laboratory manuals.
Autoimmunity -- Laboratory manuals.
Autoimmunity -- physiology.
Autoimmune Diseases -- physiopathology.
Models, Immunological.
T-Lymphocytes -- immunology.
Autoimmune diseases.
Autoimmunity.
Laboratory Manual.
Laboratory manuals.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11142667
Hidden Bibliographic Details
Other authors / contributors:Perl, Andras.
ISBN:9781607617204
160761720X
9781607617198
1607617196
Digital file characteristics:text file
PDF
Notes:Includes bibliographical references and index.
English.
Print version record.
Summary:Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease. have been developed that exhibit features of autoimmune disease. The second edition of Autoimmunity: Methods and Protocols researchers in the field detail many of the most up-to-date methods which are now commonly used to study autoimmunity. The first half the book focuses on methods and protocols used to assess immunological and biochemical pathways of diseases pathogenesis in human subjects. While the second half investigates treatment of inflammatory arthritis, experimental allergic encephalomyelitis (EAE), IDDM, scleroderma, and uveitis in animal models and assessment of genetic, immunological, and biochemical parameters underlying spontaneous or exogenous antigen-induced diseases. Written in the highly successful Methods in Molecular Biology(tm) series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Through and intuitive, Autoimmunity: Methods and Protocols, Second Edition seeks to aid scientists in the autoimmunity field to extract new meaning of old models and developing new ones.
Other form:Print version: Autoimmunity. 2nd ed. New York : Humana Press ; Springer, ©2012 9781607617198
Standard no.:10.1007/978-1-60761-720-4
Table of Contents:
  • Pathogenesis and spectrum of autoimmunity / Andras Perl
  • Mapping susceptibility gene in systemic lupus erythematosus / R. Hal Scofield and Kenneth M. Kaufman
  • Methods and protocols to study T cell signaling abnormalities in human systemic lupus erythematosus / Vaishali R. Moulton, Mindy S. Lo, and George C. Tsokos
  • Assessment of mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus / Andras Perl, Robert Hanczko, and Edward Doherty
  • Role of endocytic recycling in autoimmunity / Tiffany Telarico and Andras Perl
  • Multiparameter flow cytometry and bioanalytics for B cell profiling in systemic lupus erythematosus / Denise A. Kaminski, Chungwen Wei, Alexander F. Rosenberg, F. Eun-Hung Lee, and Ignacio Sanz
  • Experimental use of mouse models of systemic lupus erythematosus / Stanford L. Peng
  • Murine models of lupus induced by hypomethylated T cells (DNA hypomethylation and lupus ...) / Bruce Richardson, Amr H. Sawalha, Donna Ray, and Raymond Yung
  • Aspects of CNS lupus : mouse models of anti-NMDA receptor antibody mediated reactivity / Czeslawa Kowal and Betty Diamond
  • Analysis of renal mononuclear phagocytes in murine models of SLE / Ramalingam Bethunaickan, Ranjit Sahu, and Anne Davidson
  • Murine autoimmune model of rheumatoid arthritis and systemic lupus erythematosus associated with deregulated production of IL-17 and IL-21 / Partha S. Biswas, Kyuho Kang, Sanjay Gupta, Govind Bhagat, and Alessandra B. Pernis
  • Parent-into-F1 murine model in the study of lupus-like autoimmunity and CD8 cytotoxic T lymphocyte function / Kateryna Soloviova, Maksym Puliaiev, Anthony Foster, and Charles S. Via
  • Genetic approach to study lupus glomerulonephritis / Yan Ge, Michael G. Brown, Hongyang Wang, and Shu Man Fu
  • Animal models of primary biliary cirrhosis : materials and methods / Patrick S.C. Leung, Guo Xiang Yang, Amy Dhirapong, Koichi Tsuneyama, William M. Ridgway, and M. Eric Gershwin
  • Modeling innate immunity in murine skin : utilization of subcutaneous osmotic pumps for inflammatory and fibrotic skin disease / Michael Dimarzio, Giuseppina Farina, and Robert Lafyatis
  • Flow cytometric identification of fibrocytes in scleroderma lung disease / Thomas M. Russell, Erica L. Herzog, and Richard Bucala
  • Oxidative stress and beta cell dysfunction / Yaima L. Lightfoot, Jing Chen, and Clayton E. Mathews
  • Experimental autoimmune encephalomyelitis / Praveen Rao and Benjamin M. Segal
  • Mouse models of multiple sclerosis : experimental autoimmune encephalomyelitis and theiler's virus-induced demyelinating disease / Derrick P. McCarthy, Maureen H. Richards, and Stephen D. Miller
  • Pathogenesis of multiple sclerosis : what can we learn from the cuprizone model / Peter Acs and Bernadette Kalman
  • Assessing inflammatory disease at mucosal surfaces in murine genetic models / R.W. Engelman and William G. Kerr
  • Rodent models of experimental autoimmune uveitis / Rajeev K. Agarwal, Phyllis B. Silver, and Rachel R. Caspi
  • Tolerance induction via B-cell delivered gene therapy / Robert J. Rossi, Belinda M. Jackson, Ai-Hong Zhang, and David W. Scott.

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