Melanoma techniques and protocols : molecular diagnosis, treatment, and monitoring /

Melanoma techniques and protocols : molecular diagnosis, treatment, and monitoring /

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Bibliographic Details
Imprint:	Totowa, N.J. : Humana Press, ©2001.
Description:	1 online resource (xv, 366 pages) : illustrations
Language:	English
Series:	Methods in molecular medicine ; 61 Methods in molecular medicine ; 61.
Subject:	Melanoma -- Laboratory manuals. Melanoma. Neuroendocrine Tumors. Nevi and Melanomas Neuroectodermal Tumors. Neoplasms by Histologic Type Neoplasms, Nerve Tissue. Neoplasms. Neoplasms, Germ Cell and Embryonal. Disease. Melanoma. Laboratory manuals.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11150779

Hidden Bibliographic Details
Other authors / contributors:	Nickoloff, Brian J., 1953-
ISBN:	9781592591459 0896036847 9780896036840 1592591450 1280821108 9781280821103 9786610821105 6610821100 9781617371349
Notes:	Includes bibliographical references and index. Restrictions unspecified Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 English. digitized 2010 HathiTrust Digital Library committed to preserve Print version record.
Summary:	With the completion of the Human Genome Project, it is now possible to decipher the biochemical cascade of events that lead to melanoma, a virulent form of cancer that is currently at epidemic proportions worldwide. In Melanoma Techniques and Protocols: Molecular Diagnosis, Treatment, and Monitoring, a broadly diverse group of researchers and clinicians offer not only reviews of the most important recent advances in melanoma oncology, tumor immunology, and pathology, but also state-of-the-art molecular techniques for probing melanoma's basic biology. These readily reproducible methods can be used to develop diagnostic approaches, therapeutics, and status monitoring of patients suffering both early- and late-stage melanoma. With emphasis on the experimental details critical to success, each method is described in step-by-step fashion by hands-on masters, often those who have developed them in their own laboratories. Notes about potential pitfalls and troubleshooting tips on how to adapt procedures to new experimental systems are also provided. Comprehensive and highly instructive, Melanoma Techniques and Protocols: Molecular Diagnosis, Treatment, and Monitoring offers clinicians and basic scientists concerned with malignant melanoma both rich new clinical perspectives and the wide ranging experimental protocols essential for achieving more rapid breakthroughs in this near-epidemic disease.
Other form:	Melanoma techniques and protocols
Standard no.:	10.1385/1592591450

Description
Summary:	This book is about melanoma--its biology, immunology, and pathology, as well as the initial use of powerful genomic tools to study its fundamental mole- lar and genetic characteristics. The study of cancer will be profoundly impacted by the Human Genome Project. I would like to discuss some of these changes. The first draft of the human genome sequence was announced in June 2000, and we have just scratched the surface of the changes it will engender in medicine. A relevant question is what are the long-term effects of the Human Genome Project for medicine? I would argue that there are three, and each of these three point toward the view that systems biology will dominate biology and medicine of the 21st century. First, the Human Genome Project introduced a new type of s- ence--discovery science. Discovery science takes a biological system (e. g. , the genome) and defines all of its elements (e. g. , the sequences of the 24 human ch- mosomes). Thus, it creates a rich infrastructure from which the classical hypo- esis-driven science can be done more effectively. The effective integration of discovery- and hypothesis-driven science is a key for systems approaches to bi- ogy and medicine. Second, the Human Genome Project has provided a "periodic table of life.
Physical Description:	1 online resource (xv, 366 pages) : illustrations
Format:	Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliography:	Includes bibliographical references and index.
ISBN:	9781592591459 0896036847 9780896036840 1592591450 1280821108 9781280821103 9786610821105 6610821100 9781617371349