Heart physiology and pathophysiology /

Heart physiology and pathophysiology /

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Bibliographic Details
Edition:4th ed.
Imprint:San Diego, Calif. : Academic Press, 2001.
Description:1 online resource (xxi, 1261 pages) : illustrations (some color)
Language:English
Subject:
Heart -- Physiology.
Heart -- Pathophysiology.
Heart -- physiology.
Heart -- physiopathology.
Heart -- Pathophysiology.
Heart -- Physiology.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11153570
Hidden Bibliographic Details
Other uniform titles:Physiology and pathophysiology of the heart.
Other authors / contributors:Sperelakis, Nick, 1930-
ISBN:9780126569759
0126569754
9780080533889
0080533884
Notes:First 3 eds. have title: Physiology and pathophysiology of the heart.
Includes bibliographical references and index.
Print version record.
Summary:Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students. Key Features * The most comprehensive book available on this topic * Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology * Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology * Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology.
Other form:Print version: Heart physiology and pathophysiology. 4th ed. San Diego, Calif. : Academic Press, 2001 0126569754 9780126569759
Table of Contents:
  • Contributors
  • Foreword
  • Preface
  • Part I. Pumping Action and Electrical Activity of the Heart
  • 1. Sequence of Cardiac Activation and Ventricular Mechanics
  • 2. Coronary Circulation and Hemodynamics
  • 3. Neurohumoral Control of Cardiac Function
  • 4. Control of Cardiac Output and its Alterations during Exercise and in Heart Failure
  • 5. Ultrastructure of Cardiac Muscle and Blood Vessels
  • 6. Excitability and Impulse Propagation
  • 7. Electrocardiogram and Cardiac Excitation
  • 8. Gap-Junction Channels and Healing-Over of Injury
  • Part II. Cellular Electrophysiology of Heart and Vascular Smooth Muscle
  • 9. Electrogenesis of the Resting Potential
  • 10. Cardiac Action Potentials
  • 11. Electrophysiology of Vascular Smooth Muscle
  • 12. Sodium Channels
  • 13. Voltage-Dependent Calcium Channels
  • 14. Voltage-Dependent K+ Channels
  • 15. Inwardly-Rectifying K+ Channels in the Heart
  • 16. Voltage and Calcium-Activated K+ Channels of Coronary Smooth Muscle
  • 17. Ion Channels in Vascular Smooth Muscle
  • 18. Cardiac Pacemaker Currents
  • 19. Chloride Channels in Heart
  • 20. Regulation of Cardiac Ion Channels by Phosphorylation, Ca2+, Cytoskeleton, and Stretch
  • Part III. Pumps And Exchangers
  • 21. Cardiac Na+/K+ Pump
  • 22. Cardiac Na+-Ca2+ Exchanger: Pathophysiology and Pharmacology
  • 23. Na+/H+ Exchanger and pH Regulation
  • 24. Transport in Nucleus
  • 25. Sarcoplasmic Reticulum Ca2+ Transport
  • 26. Calcium Release from Cardiac Sarcoplasmic Reticulum
  • Part IV. Vascular Endothelium
  • 27. Function of Vascular Endothelium
  • 28. Ion Channels in Vascular Endothelium
  • Part V. Excitation-Contraction Coupling and Pharmacomechanical Coupling
  • 29. Electromechanical and Pharmacomechanical Coupling in Vascular Smooth Muscle Cells
  • 30. Mechanisms Regulating Cardiac Myofilament Response to Calcium
  • 31. Vascular Smooth Muscle Contraction
  • Part VI. Metabolism and Energetics
  • 32. Myocardial Energy Metabolism
  • 33. Metabolism and Energetics of Vascular Smooth Muscle
  • Part VII. Signaling Systems
  • 34. Adrenergic Receptors in the Cardiovascular System
  • 35. Cardiac Action of Angiotensin II
  • 36. ATP and Adenosine Signal Transductions
  • 37. Kinase Signaling in the Cardiovascular System
  • 38. Calcium Signaling
  • 39. Diadenosine Polyphosphate Signaling in the Heart
  • Part VIII. Developmental Changes and Aging
  • 40. Cardiac Development and Regulation of Cardiac Transcription
  • 41. Developmental Changes of Ion Channels
  • 42. Aging of the Cardiovascular System
  • 43. Changes in Autonomic Responsiveness during Development
  • Part IX. Mechanism of Action of Cardioactive Drugs
  • 44. Inotropic Mechanism in Cardiac Muscle
  • 45. Mechanisms of Action of Calcium Antagonists
  • 46. Cyclic Nucleotides and Protein Phosphorylation in Vascular Smooth Muscle Relaxation
  • 47. K+ Channel Openers
  • 48. Mode of Action of Antiarrhythmic Drugs
  • Part X. Pathophysiology
  • 49. Cellular Mechanisms of Cardioprotection
  • 50. Ischemic Preconditioning: Description, Mechanism, and Significance
  • 51. Cardioplegia and Surgical Ischemia
  • 52. Apoptosis
  • 53. Calcium Overload in Ischemia/Reperfusion Injury
  • 54. Coronary Atherosclerosis and Restenosis
  • 55. Diabetic Vascular Disease
  • 56. Angiogenesis and Coronary Collateral Circulation
  • 57. Molecular Pathophysiology of Cardiomyopathies
  • 58. Signal Transduction of Cardiac Myocyte Hypertrophy
  • 59. Electrophysiological Changes in Hypertrophy
  • 60. Molecular Basis of Inherited Long QT Syndromes and Cardiac Arrhythmias
  • 61. Molecular Mechanisms of Atrial Fibrillation
  • 62. Lipids Released during Ischemia and Arrhythmogenesis
  • 63. Ion Channels in the Heart
  • 64. Cardiac Arrhythmias: Reentry and Triggered Activity
  • 65. Myocardial Reperfusion Injury-Role of Free Radicals and Mediators of Inflammation
  • 66. Cardiac Toxicology
  • 67. Regulation of Gene Expression by Hypoxia
  • 68. Gene Transfer in Cardiovascular Therapy
  • Index

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