Transplantation immunology : methods and protocols /
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Imprint: | Totowa, N.J. : Humana Press, ©2006. |
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Description: | 1 online resource (x, 429 pages) : illustrations |
Language: | English |
Series: | Methods in molecular biology, 1064-3745 ; 333 Methods in molecular biology (Clifton, N.J.) ; v. 333. |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11155050 |
Summary: | Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection. |
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Physical Description: | 1 online resource (x, 429 pages) : illustrations |
Bibliography: | Includes bibliographical references and index. |
ISBN: | 1588295443 9781588295446 9781597451222 1597451223 9781597450492 1597450499 1280832045 9781280832048 9786610832040 6610832048 |
ISSN: | 1064-3745 ; |