Transplantation immunology : methods and protocols /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, ©2006.
Description:1 online resource (x, 429 pages) : illustrations
Language:English
Series:Methods in molecular biology, 1064-3745 ; 333
Methods in molecular biology (Clifton, N.J.) ; v. 333.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11155050
Hidden Bibliographic Details
Other authors / contributors:Hornick, Philip.
Rose, Marlene L.
ISBN:1588295443
9781588295446
9781597451222
1597451223
9781597450492
1597450499
1280832045
9781280832048
9786610832040
6610832048
Digital file characteristics:text file
PDF
Notes:Includes bibliographical references and index.
English.
Print version record.
Summary:Technical innovations in the laboratory over the past ten years have greatly improved our understanding of the immunological mechanisms of transplanted organ rejection. In Transplantation Immunology: Methods and Protocols, leading experts in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods of utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The areas of tolerance induction and reprogramming of the immune system are also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection. State of the art and highly practical, Transplantation Immunology: Methods and Protocols illuminates for clinicians and scientists-both newcomers and experts-the new world of detecting and monitoring patients' immunological responses to solid organ transplantation.
Other form:Print version: Transplantation immunology. Totowa, N.J. : Humana Press, ©2006 1588295443 9781588295446
Standard no.:10.1385/1597450499.
Description
Summary:Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.
Physical Description:1 online resource (x, 429 pages) : illustrations
Bibliography:Includes bibliographical references and index.
ISBN:1588295443
9781588295446
9781597451222
1597451223
9781597450492
1597450499
1280832045
9781280832048
9786610832040
6610832048
ISSN:1064-3745
;