Apoptosis techniques and protocols.

Apoptosis techniques and protocols.

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Bibliographic Details
Edition:	2nd ed. / edited by Andréa C. Leblanc.
Imprint:	Totowa, N.J. : Humana, ©2002.
Description:	1 online resource (xv, 250 pages) : illustrations
Language:	English
Series:	Neuromethods, 0893-2336 ; 37 Neuromethods ; 37.
Subject:	Apoptosis -- Laboratory manuals. Apoptosis -- physiology. Brain Diseases -- physiopathology. Histocytological Preparation Techniques. Neurons -- physiology. Apoptosis. Laboratory Manual. Laboratory manuals.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11155451

Hidden Bibliographic Details
Other authors / contributors:	LeBlanc, Andréa C.
ISBN:	1588290123 9781588290120 9781592591886 1592591884 1280821507 9781280821509 9786610821501 661082150X 9781617373060 1617373060 9781489938855 1489938850
Notes:	Includes bibliographical references and index. English. Print version record.
Summary:	The study of the apoptotic process has grown exponentially since the publication of the first edition of Apoptosis Techniques and Protocols for the Neuromethods series in 1997. In this greatly updated second edition, seasoned experts describe in step-by-step detail their best state-of-the-art techniques for studying neuronal cell death. These readily reproducible methods solve a wide variety of research problems, including the detection of the key proteins involved in neuronal apoptosis (Bax protein, cytochrome-c, and caspases), the direct assessment of the role of pro-apoptotic proteins in neurons by viral infections and microinjections, and the detection of proapoptotic proteins in situ. There are also hands-on methods for the study of apoptosis mechanisms in neuronal compartments, for studying synaptosis, and for establishing gene expression profiles in neurodegenerative brain tissues by using DNA microarrays. Written by investigators who have used the techniques extensively, each protocol includes tips on avoiding pitfalls, notes on the method's advantages and disadvantages, and a critical survey of the literature. Cutting-edge and highly practical, Apoptosis Techniques and Protocols, Second Edition, offers both novice and seasoned investigators a rich panoply of the productive tools they need to unravel the molecular mechanisms of neuronal cell death.
Other form:	Print version: Apoptosis techniques and protocols. 2nd ed. Totowa, N.J. : Humana, ©2002 1588290123 9781588290120
Standard no.:	10.1385/1592591884.

Description
Summary:	In this revised and expanded second edition, seasoned experts describe in step-by-step detail their best state-of-the-art techniques for studying neuronal cell death. These readily reproducible methods solve a wide variety of research problems, including the detection of the key proteins involved in neuronal apoptosis (Bax protein, cytochrome c, and caspases), the direct assessment of the role of pro-apoptotic proteins in neurons by viral infections and microinjections, and the detection of pro-apoptotic proteins in situ. There are also hands-on methods for the study of apoptosis mechanisms in neuronal compartments, for studying synaptosis, and for establishing gene expression profiles in neurodegenerative brain tissues by using DNA microarrays.
Physical Description:	1 online resource (xv, 250 pages) : illustrations
Bibliography:	Includes bibliographical references and index.
ISBN:	1588290123 9781588290120 9781592591886 1592591884 1280821507 9781280821509 9786610821501 661082150X 9781617373060 1617373060 9781489938855 1489938850
ISSN:	0893-2336 ;