DNA conjugates and sensors /
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| Imprint: | Cambridge, U.K. : RSC Pub., ©2012. |
|---|---|
| Description: | 1 online resource (xii, 303 pages) : illustrations (some color) |
| Language: | English |
| Series: | RSC biomolecular sciences, 1757-7152 ; no. 26 RSC biomolecular sciences ; 26. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11169794 |
MARC
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| 245 | 0 | 0 | |a DNA conjugates and sensors / |c edited by Keith R. Fox, Tom Brown. |
| 260 | |a Cambridge, U.K. : |b RSC Pub., |c ©2012. | ||
| 300 | |a 1 online resource (xii, 303 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a RSC biomolecular sciences, |x 1757-7152 ; |v no. 26 | |
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a "Applications of nucleic acids have developed recently to provide solutions for biosensors, diagnostic tools and as platforms for the assembly of complex structures. These developments have been possible as their base sequence can be used to assemble precise structures following simple and predictable rules. Self-assembled DNA can then be amplified using polymerase chain reaction (PCR) and this ultimately enables the preparation of synthetic nucleic acids. Their use as molecular tools or DNA-conjugates has recently been enhanced by the addition of other groups including enzymes, fluorophores and small molecules. Written by leaders in the field, this volume describes the preparation and application of these DNA-conjugates. Several have been used as sensors (aptamers, riboswitches and nanostructures) based on the ability of nucleic acids to adopt specific structures in the presence of ligands, whilst others link reporter groups such as proteins or fluorophores to RNA or DNA for detection, single molecule studies, and increasing the sensitivity of PCR. The book will interest researchers in areas related to analytical chemistry, chemical biology, medicinal chemistry, molecular pharmacology, and structural and molecular biology."-- |c Provided by publisher. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Nucleic Acid Sensors for SERRS; Quadruplexes as sensors; Click Chemistry; Fluorophore conjugates for single-molecule work; Chromophore-functionalized LNAs and their use in exploratory diagnostic applications; Small molecule-DNA conjugates; DNAzymes; Electrochemical aptamer based sensors; Small molecule-RNA conjugates; DNA pH sensors; Oligonucleotide-conjugates for detection; Oligonucleotide-conjugates as artificial Enzymes; Aptamers as diagnostic and therapeutic reagents; Subject Index | |
| 650 | 0 | |a DNA |x Synthesis. |0 http://id.loc.gov/authorities/subjects/sh85037010 | |
| 650 | 1 | 2 | |a DNA |x biosynthesis. |
| 650 | 2 | 2 | |a Aptamers, Nucleotide |x biosynthesis. |
| 650 | 2 | 2 | |a Biosensing Techniques. |
| 650 | 7 | |a Biosensors. |2 bicssc | |
| 650 | 7 | |a Analytical chemistry. |2 bicssc | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Genetics & Genomics. |2 bisacsh | |
| 650 | 7 | |a DNA |x Synthesis. |2 fast |0 (OCoLC)fst00886578 | |
| 655 | 0 | |a Electronic books. | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Fox, Keith R. |0 http://id.loc.gov/authorities/names/nb97033639 | |
| 700 | 1 | |a Brown, Tom |c (Biochemist) |0 http://id.loc.gov/authorities/names/nb2012030002 | |
| 776 | 0 | 8 | |i Print version: |t DNA conjugates and sensors. |d Cambridge : RSC Publishing, ©2012 |z 9781849734271 |w (OCoLC)821679580 |
| 830 | 0 | |a RSC biomolecular sciences ; |v 26. |0 http://id.loc.gov/authorities/names/n2006182099 | |
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| 928 | |t Library of Congress classification |a QP624 .D63 2012eb |l Online |c UC-FullText |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=e000xna&AN=519375 |z eBooks on EBSCOhost |g ebooks |i 12381542 | ||