Clinical bioinformatics /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana, ©2008.
Description:1 online resource (xi, 382 pages) : illustrations
Language:English
Series:Methods in molecular medicine ; 141
Methods in Molecular MedicinеѕǾ, 1543-1894 ; 141
Methods in molecular medicine ; 141.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11171745
Hidden Bibliographic Details
Other authors / contributors:Trent, R. J.
ISBN:9781603271486
1603271481
9781588297914
1588297918
Digital file characteristics:text file PDF
Notes:Includes bibliographical references and index.
English.
Print version record.
Summary:With the ever-increasing volume of information in clinical medicine, researchers and health professionals need computer-based storage, processing and dissemination. In Clinical Bioinformatics, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Covering such topics as gene discovery, gene function (microarrays), DNA mutation analysis, proteomics, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores its cutting edge subject. In this emerging "omics" era, Clinical Bioinformatics is the perfect guide for researchers and clinical scientists to unlock the complex, dense, and ever-growing accumulation of medical information.
Other form:Print version: Clinical bioinformatics. Totowa, N.J. : Humana, ©2008 9781588297914
Standard no.:10.1007/978-1-60327-148-6
Table of Contents:
  • In silico gene discovery / Bing Yu
  • Whole genome-wide association study using affymetrix SNP chip : a two-stage sequential selection method to identify genes that increase the risk of developing complex diseases / Howard H. Yang [and others]
  • Utilizing HapMap and tagging SNPs / Christopher A. Haiman and Daniel O. Stram
  • Measuring the effects of genes and environment on complex traits / Jennifer H. Barrett
  • Microarrays-planning your experiment / Jean Yee Hwa Yang
  • Clinical uses of microarrays in cancer research / Carl Virtanen and James Woodgett
  • Microarrays-analysis of signaling pathways / Anassuya Ramachandran [and others]
  • Microarrays-identifying molecular portraits for prostate tumors with different Gleason patterns / Alexandre Mendes, Rodney J. Scott, and Pablo Moscato
  • Microarrays for the study of viral gene expression during human cytomegalovirus latent infection / Barry Slobedman and Allen K.L. Cheung
  • Computer-assisted reading of DNA sequences / Huong Le [and others]
  • Evaluating DNA sequence variants of unknown biological significance / Scott A. Grist, Andrew Dubowsky, and Graeme Suthers
  • Developing a DNA variant database / David C.Y. Fung
  • Protein comparative sequence analysis and computer modeling / Brett D. Hambly, Cecily E. Oakley, and Piotr G. Fajer
  • Identification and characterization of microbial proteins using peptide mass fingerprinting strategies / Jonathan W. Arthur
  • Statistical analysis of image data provided by two-dimensional gel electrophoresis for discovery proteomics / Ben Crossett [and others]
  • Online resources for the molecular contextualization of disease / Chi N.I. Pang and Marc R. Wilkins
  • Web-based resources for clinical bioinformatics / Anthony M. Joshua and Paul C. Boutros
  • Developing decision support systems in clinical bioinformatics / Vitali Sintchenko and Enrico Coiera
  • eConsulting / Siaw-Teng Liaw and Peter Schattner.