Regulatory T cells /
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| Imprint: | New York : Nova Science Publishers, c2011. |
|---|---|
| Description: | 1 online resource. |
| Language: | English |
| Series: | Cell biology research progress Immunology and immune system disorders Cell biology research progress. Immunology and immune system disorders. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11173606 |
Table of Contents:
- REGULATORY T CELLS
- REGULATORY T CELLS
- Contents
- Preface
- T Helper 17 Cells Interplay with CD4+CD25highFoxp3+ Regulatory T cells in Regulating Autoimmune Inflammation
- 1. Abstract
- 2. Introduction
- 3. Comparison of the New Multi-Subset Paradigm to the old Th1-Th2 Paradigm
- 3.1. Imperfect Th1-Th2 Paradigm
- 3.2. New CD4+ Th Subsets � Tregs, Th17, Th9, Tfh, IL-10 IFN-Gamma-Secreting CD4+ T cells and CD4+CD28null T Cells
- 3.2.1. Tregs
- 3.2.2. Th17
- 3.2.3. Th9
- 3.2.4. Tfh
- 3.2.5. IL-10- IFN-gamma-secreting CD4+ T cells
- 3.2.6. CD4+CD28null T cells 4. Structural Characters of IL-17 Family Cytokines
- 5. Th17 Cells, a New Proinflammatory and Autoimmune CD4+ T Cell Subset
- 6. Wide Spectrum Effects of IL-17 on Various Cell Types and Tissues
- 6.1. Synovial Stromal Cells
- 6.2. Fibroblasts
- 6.3. Endothelial Cells
- 6.4. Vascular Smooth Muscle Cells (VSMCs)
- 6.5. Monocytic Cells and Macrophages
- 6.6. Structural Lung Cells
- 7. Signaling Pathways Initiated by Binding of IL-17 Cytokines and IL-17 Receptors
- 7.1. IL-17 Receptor Family
- 7.2. IL-17 Receptor Complex Components 7.3. IL-17 Receptor Signaling
- 8. Th17/IL-17-Mediated Inflammations
- 8.1. Experimental Autoimmune Encephalomyelitis (EAE)/Multiple Sclerosis
- 8.2. Inflammatory Skin Disease in Mice and Psoriasis in Humans
- 8.3. Inflammatory Bowel Disease (IBD) [1]
- 8.4. Experimental Arthritis/Rheumatoid Arthritis [1]
- 8.5. Atherosclerosis
- 8.6. Diabetes
- 9. Protective Roles of IL-17 in Infections
- 10. Interplay between Th17 Cells and Tregs
- 10.1. Recent Progress in Characterizing Tregs
- 10.2. Reciprocally Interconnected Th17 and Tregs10.3. Inhibition of Th17 by Tregs
- Conclusion
- References
- Human CD8 Tregs as Contender in Chronic Persisting Infections
- Abstract
- Introduction
- Treg Subsets, Markers and Plasticity
- CD8 Tregs in Human Disease
- Mechanism of Suppression by CD8+ Tregs
- The CCL4-CCR5 Axis as a New Player in CD8 Treg Mediated Suppression
- Evidence for Involvement of Tregs in Chronic Human Infectious Diseases
- Human CD4+ Tregs in Infectious Diseases
- Mycobacterial infections
- Parasitic infections
- Other bacterial infections Viral infections
- Human CD8+ Tregs in Infectious Diseases
- Mycobacterial infections
- Viral infections
- Antigen Specificity & HLA Restriction of Tregs
- Location of Tregs Suggests Significant Role in Containment of Pathogens, but Timing of Treg Activity is Crucial
- Tregs in TB Vaccination May Inhibit TB Protection: Lessons for Rational Vaccine Design
- Conclusion
- Acknowledgments
- References
- Role of Regulatory t Cells in the Treatment of Multiple Sclerosis
- Abstract
- 1. Introduction