Embryonic stem cell immunobiology : methods and protocols /

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Bibliographic Details
Imprint:	New York : Humana Press, [2013] ©2013
Description:	1 online resource (xiv, 206 pages) : illustrations
Language:	English
Series:	Methods in molecular biology, 1970-6029 ; 1029 Methods in molecular biology (Clifton, N.J.) ; v. 1029.
Subject:	Embryonic stem cells. Embryonic Stem Cells -- immunology. Embryonic stem cells.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11190695

Hidden Bibliographic Details
Other authors / contributors:	Zavazava, Nicholaus.
ISBN:	9781627034784 1627034781 1627034773 9781627034777
Digital file characteristics:	text file PDF
Notes:	Includes bibliographical references and index. English. Print version record.
Summary:	Bone marrow stem cells are the most transplanted cells worldwide. These cells are used as a replacement therapy for patients suffering from a diverse number of hematopoietic diseases and immunodeficiencies. However, the use of bone marrow cells in regenerative medicine has so far remained without much success. In the new era of pluripotent stem cells, great opportunities for establishing new therapies have opened up. The discovery of human embryonic stem cells and that of induced pluripotent (iPS) stem cells has made it possible to derive any desired tissues for regenerative medicine as iPS cell derived cells are only limited by the lack of established protocols that can be applied in humans. There is no doubt that stem cells present a new and innovative platform for establishing novel cell based therapies. The challenge is to establish new protocols that allow the successful differentiation of these cells into lineage committed cells. Embryonic Stem Cell Immunobiology: Methods and Protocols covers a variety of relevant topics, such as hematopoietic stem cells derived from ES cells, the interaction of these cells with natural killer cells or with cytotoxic T cells, and specific protocols for the derivation of hematopoietic cells and neuronal cells, to name a few. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Embryonic Stem Cell Immunobiology: Methods and Protocols serves as an ideal guide to experts and non-experts interested in different aspects of stem cells.
Other form:	Print version: Embryonic stem cell immunobiology. New York : Humana Press ; Springer, ©2013 1627034773
Standard no.:	10.1007/978-1-62703-478-4

Table of Contents:

Immune privilege of stem cells / Naoki Ichiryu and Paul J. Fairchild
Immunogenicity of in vitro maintained and matured populations : potential barriers to engraftment of human pluripotent stem cell derivatives / Chad Tang, Irving L. Weissman, and Micha Drukker
Hematopoietic and nature killer cell development from human pluripotent stem cells / Zhenya Ni, David A. Knorr, and Dan S. Kaufman
Evaluation of immunogenicity of rat ES-cell derived endothelial cells / Martina Seifert and Juliane Ladhoff
Interaction of ES cell derived neural progenitor cells with natural killer cells and cytotoxic T cells / Casimir de Rham and Jean Villard
Strategies to generate induced pluripotent stem cells / Michael Hayes and Nicholas Zavazava
Differentiation and lineage commitment of murine embryonic stem cells into insulin producing cells / Sudhanshu P. Raikwar and Nicholas Zavazava
Mouse ES cell-derived hematopoietic progenitor cells / Eun-Mi Kim, Gohar Manzar, and Nicholas Zavazava
Directed differentiation of embryonic stem cells to the T-lymphocyte lineage / Haydn C.-Y. Liang, Roxanne Holmes, and Juan Carlos Zúñiga-Pflücker
Development of hematopoietic stem and progenitor cells from mouse embryonic stem cells, in vitro, supported by ectopic human HOXB4 expression / Sandra Pilat, Sebastian Carotta, and Hannes Klump
Histone modification profiling in normal and transformed human embryonic stem cells using micro chromatin immunoprecipitation, scalable to genome-wide microarray analyses / Angelique Schnerch, Shravanti Rampalii, and Mickie Bhatia
Combined total proteomic and phosphoproteomic analysis of human pluripotent stem cells / Junjie Hou [and others]
Transcriptional regulatory mechanisms that govern embryonic stem cell fate / Satyabrata Das and Dana Levasseur.

Embryonic stem cell immunobiology : methods and protocols /

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