Pharmacogenomics and personalized medicine /
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| Imprint: | Totowa, NJ : Humana Press, ©2008. |
|---|---|
| Description: | 1 online resource (xv, 509 pages) : illustrations |
| Language: | English |
| Series: | Methods in pharmacology and toxicology, 1557-2153 Methods in pharmacology and toxicology. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11195964 |
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| 245 | 0 | 0 | |a Pharmacogenomics and personalized medicine / |c Nadine Cohen, editor. |
| 260 | |a Totowa, NJ : |b Humana Press, |c ©2008. | ||
| 300 | |a 1 online resource (xv, 509 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Methods in pharmacology and toxicology, |x 1557-2153 | |
| 505 | 0 | |a Challenges, opportunities, and evolving landscapes in pharmacogenomics and personalized medicine : an industry perspective / Nadine Cohen and Theresa Frangiosa -- Implementation of pharmacogenomic sample collection in clinical trials / Deborah Sokol Ricci and Monique Franc -- Pharmacogenomics : the regulatory environment and labeling implications / Myong-Jin Kim [and others] -- Applications of pharmacogenomics in drug discovery / Duncan McHale -- Applications of pharmacogenomics in clinical trials / Monique Franc -- Pharmacogenomics applications in drug metabolism : from genotyping to drug label-challenges? / Ann K. Daly -- The genetics of adverse drug reactions : promises and problems / Martin Armstrong -- Strategies and resources for marker selection and genotyping in genetic association studies / Nicole Soranzo, Dong-Jing Fu, and Qingqin S. Li -- Study design and statistical issues in pharmacogenetics research : from candidate genes to genome-wide screens / Nicholas J. Schork, Nathalie Malo, and Eric J. Topol -- Holy SNP, Batman! / Reyna Favis -- Predictive biomarker classifiers in the design of pivotal clinical trials / Richard Simon -- Translation of biomarkers into clinical utility / William L. Trepicchio and George Mulligan -- Pharmacogenomic study feasibility assessment and pharmaceutical business decision-making / Monique Franc and Theresa Frangiosa -- Co-development of drugs and pharmacogenomics-based diagnostics in oncology / Jeffrey S. Ross -- Pharmacogenomics applications in epilepsy / Chantal Depondt -- Pharmacogenomics in Alzheimer's disease / Ramón Cacabelos -- Pharmacogenomics applications in psychiatric disorders / Todd Lencz and Anil K. Malhotra -- Pharmacogenomics in HIV disease / Amalio Telenti -- Pharmacogenomics and cardiovascular drugs / Gérard Siest [and others] -- Pharmacogenomic applications in children / Susan F.A. Grant and Hakon Hakonarson -- Pharmacogenomics of rare and monogenic disorders / Paul D. Maher. | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a With all of the multitude of challenges facing the pharmaceutical research and development process, the industry is actively exploring the relationships between human genetics and drug responsiveness, susceptibility to disease and disease severity. In Pharmacogenomics and Personalized Medicine, leading experts from the pharmaceutical industry, the scientific community and the government provide guidance for conducting pharmacogenomic research from discovery to the market, while also presenting a realistic perspective on the challenges, practicalities and obstacles in its application. Focusing on DNA data and associated analytical methodologies this volume includes a wide array of vital, cutting-edge research. Comprehensive and timely, Pharmacogenomics and Personalized Medicine will assist novice and experienced investigators alike in the understanding of the current scientific challenges in applying pharmacogenomics to drug discovery and clinical development. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Pharmacogenomics. |0 http://id.loc.gov/authorities/subjects/sh99000126 | |
| 650 | 0 | |a Drug development. |0 http://id.loc.gov/authorities/subjects/sh97007921 | |
| 650 | 1 | 2 | |a Pharmacogenetics. |
| 650 | 2 | 2 | |a Drug Design. |
| 650 | 7 | |a Drug development. |2 fast |0 (OCoLC)fst00898670 | |
| 650 | 7 | |a Pharmacogenomics. |2 fast |0 (OCoLC)fst01060245 | |
| 653 | 0 | 0 | |a farmacologie |
| 653 | 0 | 0 | |a pharmacology |
| 653 | 0 | 0 | |a genetische variatie |
| 653 | 0 | 0 | |a genetic variation |
| 653 | 0 | 0 | |a genexpressieanalyse |
| 653 | 0 | 0 | |a genomics |
| 653 | 0 | 0 | |a individual based models |
| 653 | 1 | 0 | |a Pharmacology |
| 653 | 1 | 0 | |a Farmacologie |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Cohen, Nadine. | |
| 776 | 0 | 8 | |i Print version: |t Pharmacogenomics and personalized medicine. |d Totowa, NJ : Humana Press, ©2008 |z 9781934115046 |w (DLC) 2008925572 |w (OCoLC)213114046 |
| 830 | 0 | |a Methods in pharmacology and toxicology. |0 http://id.loc.gov/authorities/names/n2001001798 | |
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| 928 | |t Library of Congress classification |a RM301.3.G45 P422 2008 |l Online |c UC-FullText |u https://link.springer.com/10.1007/978-1-59745-439-1 |z Springer Nature |g ebooks |i 12531240 | ||