Pharmacogenomics and personalized medicine /

Saved in:

Bibliographic Details
Imprint:	Totowa, NJ : Humana Press, ©2008.
Description:	1 online resource (xv, 509 pages) : illustrations
Language:	English
Series:	Methods in pharmacology and toxicology, 1557-2153 Methods in pharmacology and toxicology.
Subject:	Pharmacogenomics. Drug development. Pharmacogenetics. Drug Design. Drug development. Pharmacogenomics.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11195964

Hidden Bibliographic Details
Other authors / contributors:	Cohen, Nadine.
ISBN:	9781597454391 1597454397 9781934115046 1934115045
Digital file characteristics:	text file PDF
Notes:	Includes bibliographical references and index. English. Print version record.
Summary:	With all of the multitude of challenges facing the pharmaceutical research and development process, the industry is actively exploring the relationships between human genetics and drug responsiveness, susceptibility to disease and disease severity. In Pharmacogenomics and Personalized Medicine, leading experts from the pharmaceutical industry, the scientific community and the government provide guidance for conducting pharmacogenomic research from discovery to the market, while also presenting a realistic perspective on the challenges, practicalities and obstacles in its application. Focusing on DNA data and associated analytical methodologies this volume includes a wide array of vital, cutting-edge research. Comprehensive and timely, Pharmacogenomics and Personalized Medicine will assist novice and experienced investigators alike in the understanding of the current scientific challenges in applying pharmacogenomics to drug discovery and clinical development.
Other form:	Print version: Pharmacogenomics and personalized medicine. Totowa, NJ : Humana Press, ©2008 9781934115046
Standard no.:	10.1007/978-1-59745-439-1

Table of Contents:

Preface
Contributors
1. Challenges, Opportunities, and Evolving Landscapes in Pharmacogenomics and Personalized Medicine: An Industry Perspective
2. Implementation of Pharmacogenomic Sample Collection in Clinical Trials
3. Pharmacogenomics: The Regulatory Environment and Labeling Implications
4. Applications of Pharmacogenomics in Drug Discovery
5. Applications of Pharmacogenomics in Clinical Trials
6. Pharmacogenomics Applications in Drug Metabolism: From Genotyping to Drug Label-Challenges?
7. The Genetics of Adverse Drug Reactions: Promises and Problems
8. Strategies and Resources for Marker Selection and Genotyping in Genetic Association Studies
9. Study Design and Statistical Issues in Pharmacogenetics Research: From Candidate Genes to Genome-Wide Screens
10. Holy SNP, Batman!
11. Predictive Biomarker Classifiers in the Design of Pivotal Clinical Trials
12. Translation of Biomarkers into Clinical Utility
13. Pharmacogenomic Study Feasibility Assessment and Pharmaceutical Business Decision-Making
14. Co-Development of Drugs and Pharmacogenomics-Based Diagnostics in Oncology
15. Pharmacogenomics Applications in Epilepsy
16. Pharmacogenomics in Alzheimer's Disease
17. Pharmacogenomics Applications in Psychiatric Disorders
18. Pharmacogenomics in HIV Disease
19. Pharmacogenomics and Cardiovascular Drugs
20. Pharmacogenomic Applications in Children
21. Pharmacogenomics of Rare and Monogenic Disorders
Index

Similar Items