Molecular evolution and phylogenetics /
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| Author / Creator: | Nei, Masatoshi. |
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| Imprint: | Oxford ; New York : Oxford University Press, ©2000. |
| Description: | 1 online resource (xiv, 333 pages) : illustrations |
| Language: | English |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11196204 |
| Summary: | During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided. |
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| Physical Description: | 1 online resource (xiv, 333 pages) : illustrations |
| Bibliography: | Includes bibliographical references (pages 301-328) and index. |
| ISBN: | 9780195350517 0195350510 9780195135848 0195135849 9780195135855 0195135857 9786610834372 6610834377 1280834374 9781280834370 |