Reverse chemical genetics : methods and protocols /

Reverse chemical genetics : methods and protocols /

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Bibliographic Details
Imprint:	New York, NY : Humana Press, ©2009.
Description:	1 online resource (xi, 272 pages) : illustrations (some color)
Language:	English
Series:	Springer protocols Methods in molecular biology, 1940-6029 ; 577 Springer protocols (Series) Methods in molecular biology (Clifton, N.J.) ; v. 577.
Subject:	Biochemical genetics. Methodology. Genetics -- Technique. Biochemistry. Pharmaceutical technology. Life sciences. Biology. Chemistry. Physical sciences. Methods Molecular Biology Laboratory Manuals Combinatorial Chemistry Techniques Genetic Techniques Investigative Techniques Publication Formats Biochemistry Technology, Pharmaceutical Genetics Biological Science Disciplines Analytical, Diagnostic and Therapeutic Techniques and Equipment Biology Publication Characteristics Chemistry Natural Science Disciplines Disciplines and Occupations Physical sciences Pharmaceutical technology Methodology Life sciences Genetics -- Technique Chemistry Biology Biochemistry Biochemical genetics Laboratory Manual Laboratory manuals Laboratory manuals.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11197921

Hidden Bibliographic Details
Other authors / contributors:	Koga, Hisashi.
ISBN:	9781607612322 1607612321 9781607612315 1607612313
Digital file characteristics:	text file PDF
Notes:	Includes bibliographical references and index. Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 English. digitized 2010 HathiTrust Digital Library committed to preserve Print version record.
Summary:	Now a major approach in the identification of certain gene product functions, reverse chemical genetics allows the identification of target genes to precede phenotypic changes created by specific small molecules. In Reverse Chemical Genetics: Methods and Protocols, expert authors introduce fundamental resources, including databases for reverse chemical genetics, as well as the modification of these cDNA resources by the most recent molecular technologies. The book explores newly established methods in addition to potentially applicable techniques that make use of specific small molecules, plus functional assays utilizing these molecules, while focusing on methods that make feasible the functional discovery and comprehensive knowledge of particular target genes. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Reverse Chemical Genetics: Methods and Protocols promises to inspire researchers to conduct their own experiments in order to progress this vital field of study.
Other form:	Print version: Reverse Chemical Genetics. Humana Press, 2009 9781607612315
Standard no.:	10.1007/978-1-60761-232-2

Description
Summary:	Now a major approach in the identification of certain gene product functions, reverse chemical genetics allows the identification of target genes to precede phenotypic changes created by specific small molecules. In Reverse Chemical Genetics: Methods and Protocols, expert authors introduce fundamental resources, including databases for reverse chemical genetics, as well as the modification of these cDNA resources by the most recent molecular technologies. The book explores newly established methods in addition to potentially applicable techniques that make use of specific small molecules, plus functional assays utilizing these molecules, while focusing on methods that make feasible the functional discovery and comprehensive knowledge of particular target genes. As a volume in the highly successful Methods in Molecular Biology(tm) series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Reverse Chemical Genetics: Methods and Protocols promises to inspire researchers to conduct their own experiments in order to progress this vital field of study.
Physical Description:	1 online resource (xi, 272 pages) : illustrations (some color)
Format:	Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliography:	Includes bibliographical references and index.
ISBN:	9781607612322 1607612321 9781607612315 1607612313
ISSN:	1940-6029 ;