Chemistry and biology of ellagitannins : an underestimated class of bioactive plant polyphenols /

Chemistry and biology of ellagitannins : an underestimated class of bioactive plant polyphenols /

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Bibliographic Details
Imprint:Hackensack, NJ : World Scientific, ©2009.
Description:1 online resource (xix, 374 pages) : illustrations (some color)
Language:English
Subject:
Plant bioactive compounds.
Phytochemicals.
Plant polyphenols.
Phytochemicals.
Plant bioactive compounds.
Plant polyphenols.
Hydrolyzable Tannins -- chemistry.
Hydrolyzable Tannins -- analysis.
Electronic books.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11199577
Hidden Bibliographic Details
Other authors / contributors:Quideau, Stéphane.
ISBN:9789812797414
9812797416
9789812797407
9812797408
1282441094
9781282441095
9786612441097
6612441097
Digital file characteristics:data file
Notes:Includes bibliographical references and index.
English.
Print version record.
Summary:This book is the first of its kind that focuses on the chemistry and biology of ellagitannins, a special class of naturally occurring polyphenols which have so far not received the attention they deserve. These polyphenolic substances are found in many plants, including numerous food sources. They not only exhibit unique structural features that fascinate most chemists who are aware of their existence, but also express remarkable biological activities that have yet to attract the interest of the pharmaceutical industry. This is surprising because ellagitannins have been identified as active pr.
Other form:Print version: Chemistry and biology of ellagitannins. Hackensack, NJ : World Scientific, ©2009 9789812797407
Table of Contents:
  • Cover
  • Contents
  • Preface
  • 1. Ellagitannins Renewed the Concept of Tannins
  • 1.1 Old and New Concepts of Tannins.
  • 1.1.1 About the chemical stability of ellagitannins.
  • 1.1.2 Definition of ellagitannins in the narrow and wider senses
  • 1.1.3 Stereochemistry of ellagitannins.
  • 1.1.4 Condensation of dehydroellagitannins with other substances
  • 1.1.5 Accumulation of an ellagitannin of specific structure in a plant.
  • 1.2 Distribution of Ellagitannins in the Plant Kingdom.
  • 1.3 Formation and Classification of Ellagitannins in Plants.
  • 1.3.1 Oxidative biological transformations from gallotannins to ellagitannins and dehydroellagitannins
  • 1.3.2 Regiospecificity of the HHDP group on the glucose core, and its correlation to plant families
  • 1.3.3 C-glycosidic ellagitannins and complex tannins.
  • 1.3.4 Oligomerization of ellagitannins leading to pentamers
  • 1.3.5 Macrocyclic oligomers
  • 1.3.6 Structural transformations of ellagitannin oligomers
  • 1.3.7 Seasonal transformations of ellagitannins in a plant
  • 1.3.8 Production of ellagitannins by tissue cultures
  • 1.4 Correlation of Ellagitannins of Various Oxidation Stages with Plant Evolution Systems.
  • 1.4.1 Classification of hydrolyzable tannins based on the oxidation stages of their polyphenolic functions
  • 1.4.2 Correlation of the oxidation stages with Cronquist8217;s system of plant evolution
  • 1.4.3 Isolation of oxidized ellagitannin oligomers in specific plant orders
  • 1.5 Main Ellagitannin-Rich Medicinal Plants
  • 1.6 Properties and Primary Activities of Ellagitannins.
  • 1.6.1 Reduction, stabilization and precipitation of other substances by tannins, and solubilization of precipitates by excess tannin
  • 1.6.2 Indexes of tannin binding activity and reversal of tannin biological activities
  • 1.6.3 Antioxidant activities
  • 1.7. Biological and Pharmacological Activities
  • 1.7.1 Antiviral, antimicrobial and immunomodulatory activities
  • 1.7.2 Antitumor activities
  • 1.7.3 Induction of apoptosis.
  • 1.7.4 Effects on liver functions and others.
  • 1.7.5 Absorption and metabolism of ellagitannins in animals
  • 1.8 Bibliography
  • 2. Structural Diversity and Antimicrobial Activities of Ellagitannins
  • 2.1 Monomeric Ellagitannins
  • 2.1.1 Primary ellagitannins (HHDP esters)
  • 2.1.2 Dehydroellagitannins
  • 2.1.3 Modified dehydroellagitannins
  • 2.1.4 C-Glycosidic ellagitannins
  • 2.1.5 Complex tannins (hybrids bearing a flavan-3-ol moiety)
  • 2.2 Oligomeric Ellagitannins
  • 2.2.1 Oligomers linked with a dehydrodigalloyl group.
  • 2.2.2 Oligomers linked with valoneoyl and dehydrovaloneoyl groups
  • 2.2.3 Oligomers linked with an isomeric valoneoyl group.
  • 2.2.4 C-Glycosidic ellagitannin oligomers.
  • 2.3 Chemotaxonomic Significance of Oligomeric Ellagitannins
  • 2.4 Antimicrobial Effects of Ellagitannins
  • 2.4.1 Variation of antibacterial effects according to bacterial species.
  • 2.4.2 Effects on Helicobacter pylori.
  • 2.4.3 Effects on antibiotic-resistant bacteria
  • 2.4.4 Effects on Leishmania donovani.
  • 2.5 Bibliography
  • 3. Biosynthesis of Ellagitannins: Old Ideas and New Solutions
  • 3.1 Introduction
  • 3.2 Principal Structures and Definitions.
  • 3.3 Gallic Acid, the Principal Phenolic Unit
  • 3.4 Biosynthesis of 946;-Glucogallin
  • 3.5 8216;Simple8217; Galloylglucose Esters: the Route to Pentagalloylglucose
  • 3.6 The Side Route to Gallotannins
  • 3.7 Biosynthesis of Ellagitannins
  • 3.7.1 Search for pentagalloylglucose oxi.

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