Phosphatase modulators /

Phosphatase modulators /

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Bibliographic Details
Imprint:	New York : Humana Press, [2013] ©2013
Description:	1 online resource (x, 315 pages) : illustrations (some color)
Language:	English
Series:	Methods in molecular biology, 1940-6029 ; volume no. 1053 Methods in molecular biology (Clifton, N.J.) ; v. 1053.
Subject:	Phosphatases. Phosphoprotein phosphatases. Drugs -- Design. Esterases. Hydrolases. Enzymes. Publication Formats Esterases Hydrolases Publication Characteristics Enzymes Enzymes and Coenzymes Chemicals and Drugs Laboratory Manuals Phosphoric Monoester Hydrolases Phosphoprotein Phosphatases Drug Design Hydrolases Esterases Enzymes Drugs -- Design Phosphatases Phosphoprotein phosphatases Laboratory Manual Laboratory manuals.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11200452

Hidden Bibliographic Details
Other authors / contributors:	Millán, José Luis, editor.
ISBN:	9781627035620 1627035621 9781627035613 1627035613
Digital file characteristics:	text file PDF
Notes:	Includes bibliographical references and index. English. Online resource; title from PDF title page (Springer, viewed July 17, 2013).
Summary:	Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one "how to" manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making "go/no-go" decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results. Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts
Other form:	Print version: Phosphatase modulators. New York : Humana Press ; Springer, ©2013 1627035613
Standard no.:	10.1007/978-1-62703-562-0

Description
Summary:	<p>Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one "how to" manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making "go/no-go" decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results.</p> <p> </p> Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts.
Physical Description:	1 online resource (x, 315 pages) : illustrations (some color)
Bibliography:	Includes bibliographical references and index.
ISBN:	9781627035620 1627035621 9781627035613 1627035613
ISSN:	1940-6029 ;