Lung cancer : a comprehensive overview /
Saved in:
| Imprint: | New York : Nova Biomedical, [2013] |
|---|---|
| Description: | 1 online resource |
| Language: | English |
| Series: | Cancer etiology, diagnosis and treatments Cancer etiology, diagnosis, and treatments. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11201050 |
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| 072 | 7 | |a HEA |x 039030 |2 bisacsh | |
| 072 | 7 | |a MED |x 062000 |2 bisacsh | |
| 245 | 0 | 0 | |a Lung cancer : |b a comprehensive overview / |c Kathy Gately, editor. |
| 264 | 1 | |a New York : |b Nova Biomedical, |c [2013] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Cancer etiology, diagnosis and treatments | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | |a Description based on print version record. | ||
| 505 | 0 | |a Intro -- LUNG CANCER: A COMPREHENSIVE OVERVIEW -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Chapter I: The Pathology of Lung Cancer -- Abstract -- Introduction -- Common Lung Cancers -- Adenocarcinoma -- Squamous Cell Carcinoma -- Distinction of Adenocarcinoma from Squamous Cell Carcinoma on Biopsy Specimens -- Small Cell Carcinoma -- Large Cell Carcinoma -- Neuroendocrine Tumours -- Metastases -- Other Tumours -- Staging -- Molecular Analysis -- Conclusion -- References -- Chapter II: Introduction to Lung Cancer, its Epidemiology and Diagnosis -- Abstract -- Introduction -- International Variation in Lung Cancer Prevalence -- Age and Lung Cancer -- Host Factors and Lung Cancer Risk from Smoking -- Gender Differences in Lung Cancer Incidence -- Race -- Second-Hand Tobacco Smoke -- Non-Smoking Related Exposures for Lung Cancer -- Radon -- Occupational Exposures -- Air Pollutants -- Body Mass Index as a Risk Factor for Lung Cancer -- Non-Cancer Lung Disease -- Genetic Factors in Lung Cancer Risk -- Diagnosis of Lung Cancer -- Symptomatic Lung Cancer Detection -- Asymptomatic Disease: Incidental and Screening Detection -- Diagnosis of Suspected Lung Cancer -- Diagnosis Based on Imaging Characteristics -- Diagnostic Strategies -- Conclusion -- References -- Chapter III: The Effect of Smoking Habit Intensity, Occupation and Diet on Lung Cancer Risk in Males -- Abstract -- Introduction -- Risk Factors -- Tobacco Smoking -- Occupational Exposure -- Diet -- Case Report -- Methods -- Results -- Conclusion -- References -- Chapter IV: Lung Cancer: Treatment in Early Stage -- Abstract -- Introduction -- Adjuvant and Neoadjuvant Therapy for Resectable Non-Small Cell Lung Cancer -- Evidence for Adjuvant CT -- Preoperative CT for Early-Stage NSCLC -- The Role of Adjuvant RT. | |
| 505 | 8 | |a Future Directions: Targeted Therapies and Genetic Predictive and Prognostic Biomarkers -- Conclusion -- References -- Chapter V: Lung Cancer: Treatment in Advanced Stages -- Abstract -- Introduction -- Treatment of Stage III Non-Small Cell Lung Cancer (NSCLC) -- Treatment of Metastatic Non-Small Cell Lung Cancer -- Initial Systemic Therapy for Advanced NSCLC without an EGFR Mutation or the ALK Fusion Oncogene -- Initial Treatment with Targeted Agents -- Second Line Therapy -- Conclusion -- References -- Chapter VI: Management of Stage III N2 NSCLC -- Abstract -- Introduction -- Staging -- Proving N2 Disease -- Treatment -- Goals of Neoadjuvant Therapy -- Current Controversies -- Conclusion -- References -- Chapter VII: Targeted Therapies in Non-Small Cell Lung Cancer -- Abstract -- Introduction -- Targeted Therapy in Lung Cancer -- EGFR -- Targeting EGFR -- VEGF and VEGFR -- Targeting VEGFR with Bevacizumab -- Targeting VEGFR with TKIs -- EML4-ALK -- Targeting EML4-ALK -- KRAS -- Targeting KRAS -- HER2 -- Targeting HER2 -- B-RAF -- Targeting B-RAF -- C-Met -- Targeting C-Met -- PI3K -- Targeting PI3K -- MEK -- Targeting MEK -- PI3K and MEK Co-Targeted Inhibition -- IGF1R -- Targeting IGF1R -- The Future of Targeted Therapy -- Conclusion -- References -- Chapter VIII: Molecular Mechanisms of Cisplatin Resistance in Lung Cancer -- Abstract -- Introduction -- Resistance Mechanisms -- Epigenetic Regulation and Cisplatin Resistance -- Novel Strategies for Overcoming Cisplatin Resistance -- Conclusion -- References -- Chapter IX: Inflammation in Lung Carcinogenesis -- Abstract -- Introduction -- Cancer Related Inflammation -- Lung Cancer and Inflammation -- Inflammatory Mediators In Lung Cancer -- Targeting Inflammation as a Therapeutic Option -- Conclusion -- References. | |
| 505 | 8 | |a Chapter X: The Link between Chronic Obstructive Pulmonary Disease and Lung Cancer: Novel Molecular Insights -- Abstract -- Introduction -- Hazardous Effects of Cigarette Smoking -- Carcinogenic Compounds in the Side-Stream Smoke -- Chronic Inflammation in COPD and Lung Cancer -- Genetics of COPD and Lung Cancer -- Epigenetic Phenomena and Cigarette Smoke -- Conclusion -- References -- Chapter XI: Diagnosis, Treatment and Follow-Up of Neoplastic Pericardial Disease in Lung Cancer -- Abstract -- Introduction -- Diagnosis -- Treatment -- Conclusion -- References -- Chapter XII: The Role of Claudin Proteins in Lung Tumorigenesis -- Abstract -- Introduction -- Claudin Family Proteins -- Post-Translational Modifications of Tight Junction Proteins -- Tight Junction Proteins and Lung Cancer -- Crosstalk of Claudins and Occludin with Other Signaling Pathways in Lung Cancer -- Claudins as Therapeutic Targets -- Conclusion -- Acknowledgments -- References -- Chapter XIII: The Role of the Arachidonic Acid Pathway in NSCLC Development and Progression: Novel Approaches for Therapeutic Intervention -- Abstract -- Introduction -- 1. Arachidonic Acid Metabolism: Generation and Classification of Eicosanoids -- 2. Altered Expression of Arachidonic Acid Signalling in NSCLC -- 3. Effect of the Arachidonic Acid Pathway on Tumour Cell Signalling and Proliferation -- 4. Arachidonic Acid Mediated Regulation of Tumour Cell Death -- 5. The Role of Arachidonic Acid Signalling in NSCLC Tumour Angiogenesis -- 6. Regulation of Adhesion, Migration and Invasion of NSCLC by Arachidonic Acid Pathways -- 7. Modulation of the Immune System in NSCLC by Arachidonic Acid -- 8. Targeting Arachidonic Acid Pathways Using Pharmacological and Natural Agents -- Conclusion -- References -- Index. | |
| 650 | 0 | |a Lungs |x Cancer. |0 http://id.loc.gov/authorities/subjects/sh85078900 | |
| 650 | 1 | 2 | |a Lung Neoplasms. |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Cancer. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Oncology. |2 bisacsh | |
| 650 | 7 | |a Lungs |x Cancer. |2 fast |0 (OCoLC)fst01003756 | |
| 655 | 0 | |a Electronic books. | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Gately, Kathy, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Lung cancer |d New York : Nova Science Publishers, [2013] |z 162618447X (hbk.) |w (DLC) 2013935077 |
| 830 | 0 | |a Cancer etiology, diagnosis, and treatments. |0 http://id.loc.gov/authorities/names/n2009183163 | |
| 903 | |a HeVa | ||
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| 928 | |t Library of Congress classification |a RC280.L8 |l Online |c UC-FullText |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=e000xna&AN=607834 |z eBooks on EBSCOhost |g ebooks |i 12393157 | ||