International review of cell and molecular biology /
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| Edition: | First edition. |
|---|---|
| Imprint: | San Diego : Academic Press, 2014. |
| Description: | 1 online resource (408 pages) : illustrations (some color). |
| Language: | English |
| Series: | International review of cell and molecular biology, 1937-6448 ; volume three hundred and nine |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11224366 |
Table of Contents:
- Front Cover; International Review of Cell and Molecular Biology; Copyright; Contents; Contributors; Chapter One: Mouse Primordial Germ Cells: A Reappraisal; 1. Introduction; 2. Current Model of the Origin of Primordial Germ Cells (PGCs) and Segregation from Soma; 3. Flaws in Current Model of PGC Origin and Segregation; 3.1. Lineage continuity and segregation of PGCs from soma: Criteria and evidence; 3.2. PGC trajectory and ``markers ́ ́ of PGCs; 3.2.1. AP activity and PGC trajectory; 3.2.1.1. AP activity: Embryonic germ cells; 3.2.1.2. AP activity: Cytoplasmic ``spot ́ ́; 3.2.2. Tnap.
- 3.2.3. OCT-3/43.2.4. PRDM1; 3.2.5. STELLA; 3.2.6. IFITM3; 3.2.7. NANOG; 3.3. Errant PGCs; 4. Comparison of Mammalian Germline Program to That Across Metazoa; 5. Embryonic-Extraembryonic Interface and Fetal-Umbilical Connection: PGCs and ACD; 6. Loss/Mislocalization of PGCs and Associated Posterior Defects; 6.1. Mir-290-295; 6.2. Prdm14; 7. Perspectives; 7.1. Alternative models; 7.2. Where we are now; 8. Conclusions; Acknowledgments; References; Chapter Two: Microtubule Plus-End Tracking Proteins and Their Roles in Cell Division; 1. Introduction; 2. Microtubules in Cell Division.
- 2.1. Mitotic entry2.2. Prometaphase-metaphase transition; 2.3. Metaphase; 2.4. Metaphase-anaphase transition; 2.5. Mitotic exit and cytokinesis; 3. Families of Microtubule Plus-End-Tracking Proteins (TIPs); 3.1. CLIP family; 3.2. EB family; 3.3. CLASP family; 3.4. APC family; 3.5. Motor proteins; 3.5.1. Kinesins; 3.5.2. Dynein; 3.6. Lis1; 3.7. Kinesin-13 family; 3.8. TOG family; 3.9. Other +TIPs; 4. Recognition of Microtubule Plus Ends by +TIPs; 4.1. Recognizing the microtubule plus end; 4.2. Copolymerization; 4.3. Diffusion versus motor-based transport; 4.4. Hitchhiking.
- 4.5. Turnover at microtubule plus end5. +TIPs in Mitosis; 5.1. +TIPs in mitotic spindle organization and positioning; 5.2. +TIPs at mitotic centrosome; 5.3. +TIPs at kinetochore; 5.4. +TIPs regulation during mitosis; 5.5. +TIPs in mitotic exit and cytokinesis; 6. Concluding Remarks; Acknowledgments; References; Chapter Three: Unicellular Eukaryotes as Models in Cell and Molecular Biology: Critical Appraisal of Their Past and Future ... ; 1. Introduction; 2. What is Special About Unicellular Models; 2.1. Unicellular models; 2.1.1. Dictyostelium (Amoebozoa, Mycetozoa).
- 2.1.2. Paramecium and Tetrahymena (Alveolata, Ciliata)2.1.3. Chlamydomonas (Chlorophyta, Volvocales); 2.1.4. Yeast (Fungi, Ascomycota); 2.2. Unicellular models: Examples, pitfals, and perspectives; 3. Unicellular Models for Organelle Biogenesis; 3.1. Biogenesis of mitochondria in yeast; 3.2. Biogenesis of secretory organelles, cilia, and flagella; 3.3. Phagocytotic pathway; 3.4. Qualifying for model system by precise timing; 3.4.1. Cilia; 3.4.2. Exocytosis and exo-/endocytosis coupling; 3.4.3. Phagocytotic cycle; 3.5. Free-living forms as models for pathogenic forms.