Epigenetics : mechanisms, functions and human effects /

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Bibliographic Details
Imprint:New York : Nova Science Publishers, ©2010.
Description:1 online resource (xiii, 303 pages) : illustrations (some color)
Language:English
Series:Genetics--research and issues series
Genetics--research and issues series.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11234029
Hidden Bibliographic Details
Other authors / contributors:Pintér, Balázs.
Mészáros, Zsolt.
ISBN:9781616688738
1616688734
9781607414544
1607414546
Notes:Includes bibliographical references and index.
English.
Print version record.
Summary:"Epigenetics refers to DNA and chromatin modifications that persist from one cell division to the next despite a lack of change in the underlying DNA sequence. It is an emergent field since its implication in physiological and disease processes is now widely accepted. The effects of epigenetics play an important role in development but can also arise stochastically with aging. Since their discovery in 1983, cancer-associated epigenetic changes have become accepted as playing a pivotal role in carcinogenesis, in conjunction with classical genomic mutations. Thus it is now well established that an epigenetic mechanism underlies the pathogenesis of cancer and there is evidence implicating epigenetic factors in the pathogenesis of idiopathic mental disorders such as schizophrenia, bipolar disorder and even autism. This new book gathers the latest research from around the globe in this field of study and related topics."--Publisher's description.
Other form:Print version: Epigenetics. New York : Nova Science Publishers, ©2010 9781607414544

MARC

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245 0 0 |a Epigenetics :  |b mechanisms, functions and human effects /  |c Balázs Pintér and Zsolt Mészáros, editors. 
260 |a New York :  |b Nova Science Publishers,  |c ©2010. 
300 |a 1 online resource (xiii, 303 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Genetics--research and issues series 
504 |a Includes bibliographical references and index. 
505 0 |a Techniques in cancer epigenetics / Michele Cummings and Laura Smith -- Melatonin : epigenetic mechanisms in cancer inhibition / Ahmet Korkmaz and Russel J. Reiter -- The epigenetic (re)programming of phenotypic differences in behavior / Patrick O. McGowan, Michael J. Meaney and Moshe Szyf -- Role of H3 phosphorylation in different biological processes in normal and disease states / Geneviève P. Delcuve, Paula S. Espino and James R. Davie -- The role of DNA methylation in colorectal cancer / Ivana Fridrichova -- Epigenetic clues to arthritic diseases / Helmtrud I. Roach and Emma L. Williams -- Evolution of the Fpg/Nei family of DNA glycosylases / Dorothy E. Pumo [and others] -- The clinical and etiological relevance of MLH1 promoter hypermethylation in ovarian tumors / Tuya Pal and O. Thomas Mueller -- Epigenetic role in longevity echoes conserved stress survival strategies / Joan Smith Sonneborn -- Epigenetics and neurodegeneration : a connection overlooked / Sueli C.F. Marques, Clâaudia M.F. Pereira and Tiago F. Outeiro -- DNA methylation changed by 5-azacytidine can affect normal fetal and placental development / Ljiljana Serman [and others] -- Epigenetic analysis in breast cancer progression / Frank A. Orlando, Lisa M. Dyer and Kevin D. Brown -- Cancer epigenetics / Frank A. Orlando, Berna Demircan and Kevin D. Brown. 
520 |a "Epigenetics refers to DNA and chromatin modifications that persist from one cell division to the next despite a lack of change in the underlying DNA sequence. It is an emergent field since its implication in physiological and disease processes is now widely accepted. The effects of epigenetics play an important role in development but can also arise stochastically with aging. Since their discovery in 1983, cancer-associated epigenetic changes have become accepted as playing a pivotal role in carcinogenesis, in conjunction with classical genomic mutations. Thus it is now well established that an epigenetic mechanism underlies the pathogenesis of cancer and there is evidence implicating epigenetic factors in the pathogenesis of idiopathic mental disorders such as schizophrenia, bipolar disorder and even autism. This new book gathers the latest research from around the globe in this field of study and related topics."--Publisher's description. 
588 0 |a Print version record. 
546 |a English. 
650 0 |a Cancer  |x Etiology.  |0 http://id.loc.gov/authorities/subjects/sh88001076 
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650 1 2 |a Neoplasms  |x genetics. 
650 2 2 |a Epigenesis, Genetic. 
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650 7 |a HEALTH & FITNESS  |x Diseases  |x Cancer.  |2 bisacsh 
650 7 |a Cancer  |x Etiology.  |2 fast  |0 (OCoLC)fst00845361 
650 7 |a Cancer  |x Genetic aspects.  |2 fast  |0 (OCoLC)fst00845368 
650 7 |a Epigenesis.  |2 fast  |0 (OCoLC)fst00914128 
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650 7 |a Health & Biological Sciences.  |2 hilcc 
650 7 |a Oncology.  |2 hilcc 
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700 1 |a Pintér, Balázs. 
700 1 |a Mészáros, Zsolt. 
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