The blood-brain and other neural barriers : reviews and protocols /

The blood-brain and other neural barriers : reviews and protocols /

Saved in:

Bibliographic Details
Imprint:	New York : Humana Press, ©2011.
Description:	1 online resource (xiv, 502 pages) : illustrations (some color)
Language:	English
Series:	Springer protocols Methods in molecular biology, 1940-6029 ; v. 686 Springer protocols (Series) Methods in molecular biology (Clifton, N.J.) ; v. 686.
Subject:	Blood-brain barrier. Blood-Brain Barrier. Blood-Nerve Barrier. Blood-brain barrier.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11234045

Hidden Bibliographic Details
Other authors / contributors:	Nag, Sukriti.
ISBN:	9781607619383 1607619385 9781607619376 1607619377
Digital file characteristics:	text file
Notes:	Includes bibliographical references and index. English.
Summary:	Evolving technologies starting with tracer studies, and more recently with genomics and proteomics, have provided novel information about the molecular properties of cerebral endothelium and astrocytes; however, further studies must be done in animal models of neurological diseases and in humans to get a clearer understanding of the pathogenesis of blood-brain barrier (BBB) breakdown in nervous system diseases. In The Blood-Brain and Other Neural Barriers: Reviews and Protocols, experts in the field present a series of cutting-edge protocols which can be used to study the barriers. Opening with detailed information on components of the neurovascular unit as well as the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, the book continues with meticulous techniques to image the barriers in humans and experimental animals, followed by cutting-edge molecular techniques to study the BBB and novel models to study the barriers, and it concludes with techniques for the delivery of therapeutic agents across the BBB. Written in the highly successful Methods in Molecular Biology series format, protocol chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, The Blood-Brain and Other Neural Barriers: Reviews and Protocols will aid the research efforts of not only graduate students but also more experienced investigators and support future studies of these vital systems.
Other form:	Print version: Blood-brain and other neural barriers. New York, NY : Humana, ©2011 9781607619376
Standard no.:	10.1007/978-1-60761-938-3

Description
Summary:	Evolving technologies starting with tracer studies, and more recently with genomics and proteomics, have provided novel information about the molecular properties of cerebral endothelium and astrocytes; however, further studies must be done in animal models of neurological diseases and in humans to get a clearer understanding of the pathogenesis of blood-brain barrier (BBB) breakdown in nervous system diseases. In The Blood-Brain and Other Neural Barriers: Reviews and Protocols, experts in the field present a series of cutting-edge protocols which can be used to study the barriers. Opening with detailed information on components of the neurovascular unit as well as the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, the book continues with meticulous techniques to image the barriers in humans and experimental animals, followed by cutting-edge molecular techniques to study the BBB and novel models to study the barriers, and it concludes with techniques for the delivery of therapeutic agents across the BBB. Written in the highly successful Methods in Molecular Biology(tm) series format, protocol chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, The Blood-Brain and Other Neural Barriers: Reviews and Protocols will aid the research efforts of not only graduate students but also more experienced investigators and support future studies of these vital systems.
Physical Description:	1 online resource (xiv, 502 pages) : illustrations (some color)
Bibliography:	Includes bibliographical references and index.
ISBN:	9781607619383 1607619385 9781607619376 1607619377
ISSN:	1940-6029 ;