Brain energy metabolism /

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Bibliographic Details
Imprint:	New York, NY : Humana Press, 2014.
Description:	1 online resource (xiv, 368 pages) : illustrations (some color)
Language:	English
Series:	Neuromethods, 0893-2336 ; 90 Neuromethods ; 90.
Subject:	Brain -- Metabolism. Energy metabolism. Brain -- metabolism Brain Chemistry -- physiology Energy Metabolism Brain -- Metabolism Energy metabolism Laboratory Manual Laboratory manuals.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11236361

Hidden Bibliographic Details
Other authors / contributors:	Hirrlinger, Johannes, editor. Waagepetersen, Helle S., editor.
ISBN:	9781493910595 1493910590 1493910582 9781493910588 9781493910588
Notes:	Includes index. Includes bibliographical references and index. Online resource; title from PDF title page (SpringerLink, viewed October 2, 2014).
Summary:	Brain Energy Metabolism addresses its challenging subject by presenting diverse technologies allowing for the investigation of brain energy metabolism on different levels of complexity. Model systems are discussed, starting from the reductionist approach like primary cell cultures which allow assessing of the properties and functions of a single brain cell type with many different types of analysis, however, at the expense of neglecting the interaction between cell types in the brain. On the other end, analysis in animals and humans in vivo is discussed, maintaining the full complexity of the tissue and the organism but making high demands on the methods of analysis. Written for the popular Neuromethods series, chapters include the kind of detailed description and key implementation advice that aims to support reproducible results in the lab. Meticulous and authoritative, Brain Energy Metabolism provides an ideal guide for researchers interested in brain energy metabolism with the hope of stimulating more research in this exciting and very important field.
Other form:	Print version: Brain energy metabolism.
Standard no.:	10.1007/978-1-4939-1059-5

Table of Contents:

Determination of CO2 Production in Subcellular Preparations like Synaptosomes and Isolated Mitochondria Using 14C-Labeled Substrates and Radioactive CO2 Measurements
Transport of Lactate: Characterization of the Transporters Involved in Transport at the Plasma Membrane by Heterologous Protein Expression in Xenopus Oocytes
Primary Cultures of Astrocytes and Neurons as Model Systems to Study the Metabolism and Metabolite Export from Brain Cells
Metabolic Mapping of Astrocytes and Neurons in Culture Using Stable Isotopes and Gas Chromatography-Mass Spectrometry (GC-MS)
Metabolic Flux Analysis Tools to Investigate Brain Metabolism In Vitro
Fluorescent Nanosensor Based Flux Analysis: Overview and the Example of Glucose
Mitochondrial Bioenergetics Assessed by Functional Fluorescence Dyes
RNA Interference as a Tool to Selectively Down-Modulate Protein Function
Localizing and Quantifying Metabolites In Situ with Luminometry: Induced Metabolic Bioluminescence Imaging (imBI)
A Chip Off the Old Block: The Brain Slice as a Model for Metabolic Studies of Brain Compartmentation and Neuropharmacology
Integrated Measurements of Electrical Activity, Oxygen Tension, Blood Flow, and Ca2+-Signaling in Rodents In Vivo
Measuring Cerebral Hemodynamics and Energy Metabolism by Near-Infrared Spectroscopy
Compartmental Analysis of Metabolism by 13C Magnetic Resonance Spectroscopy
Positron Emission Tomography of Brain Glucose Metabolism with [18F]Fluorodeoxyglucose in Humans.

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