Natural killer cells /

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Bibliographic Details
Imprint:	Cham : Springer, 2016.
Description:	1 online resource (viii, 247 pages)
Language:	English
Series:	Current topics in microbiology and immunology, 0070-217X ; volume 395 Current topics in microbiology and immunology ; 395.
Subject:	Killer cells. Killer Cells, Natural. Killer cells. Electronic books.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11252865

Hidden Bibliographic Details
Other authors / contributors:	Vivier, E., editor. Di Santo, James, editor. Moretta, Alessandro, editor.
ISBN:	9783319239163 3319239163 9781493936823 1493936824 9783319239156 3319239155
Digital file characteristics:	text file PDF
Notes:	Includes index. Includes bibliographical references and index. English. Online resource; title from PDF title page (SpringerLink, viewed February 23, 2016).
Summary:	To celebrate the 40th anniversary of the discovery of Natural Killer (NK) cells, this volume focuses on the recent advances in our understanding of NK cell development and differentiation and their acquisition of functional properties, as well as the latest models for NK-cell analysis in mice and applications in clinical medicine. NK cells have travelled a circuitous path from their initial description as 'spontaneous killers' (for some simply an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of action in immune defense and an important mediator of immune reactivity in health and disease. Together, these reviews provide a timely and concise picture of the evolution of NK cells as essential agents in immunity and as potent weapons against disease. This book offers an appealing and insightful resource for scientists and clinicians.
Other form:	Print version: Natural killer cells. Cham : Springer, 2016 3319239155 9783319239156
Standard no.:	10.1007/978-3-319-23916-3

Table of Contents:

Transcriptional control of NK cells
Development, Homeostasis and Heterogeneity of NK cells and ILC1
Diversification and functional specialization of human NK cell subsets
Dynamic regulation of NK cell responsiveness
Sweet is the memory of past troubles: NK cells remember
Lessons from NK cell deficiencies in the mouse
Probing human NK cell biology using Human Immune System (HIS) mice
Haploidentical-Haematopoietic Stem Cell Transplantation: role of NK cells and effect of cytomegalovirus infections
The past, present and future of NK cells in hematopoietic cell transplantation and adoptive transfer
NK cells and Cancer Immunoediting.

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