RNA/DNA and cancer /
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Author / Creator: | Sinkovics, Joseph G., 1924- author. |
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Imprint: | Cham : Springer, [2016] |
Description: | 1 online resource : illustrations |
Language: | English |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11254315 |
Table of Contents:
- Preface. Introductions. I THE PRIMORDIAL RNA/DNA COMPLEX EVOLVING
- The Primordial Genes Are Conserved as Stem Cell Genes and Proto-Oncogenes
- The First Cells Ascend
- Eukaryotic Single Cells and the First Cell Communities Then and Now
- A Highly Effective Immune System Predating Adaptive Immunity
- Elements of Adaptive Immunity Self-Assemble
- The RNA/DNA Complex at Work
- YY Proteins
- Elusive Alleles
- The Long Trajectory of the IGF-like Receptor and Its Ligands
- Primordial Fused Genes Become Oncogenes and Encode Oncoproteins
- Performance in the Laboratory
- Inbuilt Errors not yet Corrected
- Errors or Inherent Attributes for the Sustenance of Unicellular Life
- Viral Genomic Insertions into the Host Cell's Genome
- Viral and Cellular Proteins Interact
- Light Cast to Broken DNA, Its Repair, and Consequences
- Undisciplined Introns
- Elementary Epigenomics
- RNA/DNA: Bioengineers Supreme
- II THE ONCOGENOME
- Seamless Unity of the Nucleus and Cytoplasm: the Membranes Are Permeable
- Endogenously Initiated Immortalization is Welcome. Enforced Carcinogenesis by Exogenous Alien Initiator Is Resisted
- A Condensed Compendium
- "Malignant Transformation"
- III THE HUMAN CEREBRAL CORTICAL DNA AGAINST CANCER CELL DNA
- Will the Human Cerebral Cortex Subdue the Oncogenome?- In Self-Defense, the Cancer Cell Reactivates Its Primordial Genome Loaded with Proviruses in Order to Mobilize All Its Remaining Survival Pathways
- The Cancer Cell Viewed as a Unicellular Parasite (an Amoeba)
- Astute Observers Withstand Derision
- "Making Cancer History" at M.D. Anderson Hospital
- SUMMARY
- Appendix 1
- Appendix 2
- Index.