OCT in central nervous system diseases : the eye as a window to the brain /

Saved in:
Bibliographic Details
Imprint:Cham : Springer, [2016]
Description:1 online resource : illustrations
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11254341
Hidden Bibliographic Details
Other authors / contributors:Grzybowski, Andrzej, 1968- editor.
Barboni, Piero (Ophthalmologist), editor.
ISBN:9783319240855
3319240854
3319240838
9783319240831
9783319240831
Digital file characteristics:text file
PDF
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (EBSCO, viewed April 6, 2016).
Summary:This book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promising tool for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. The disorders considered include multiple sclerosis, Parkinsonℓ́ℓs disease, Alzheimerℓ́ℓs disease, intracranial hypertension, Friedreichℓ́ℓs ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. As well as being a valuable tool for diagnosis of many retinal diseases and monitoring of surgical and medical treatment, OCT allows study of the retinal nerve fiber layer (RNFL) containing the axons of the retinal ganglion cells, which form the optic nerves, chiasm, and optic tracts. Since retinal axons are nonmyelinated until they penetrate the lamina cribrosa, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. It is for this reason that OCT has been applied in various areas of neurology over the past decade, becoming a hot topic and generating great enthusiasm among neurologists and ophthalmologists. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the ℓ́ℓwindow to the brainℓ́ℓ.
Other form:Printed edition: 9783319240831
Standard no.:10.1007/978-3-319-24085-5

Similar Items