Computational design of ligand binding proteins /
Saved in:
| Imprint: | New York : Humana Press : Springer, ©2016. |
|---|---|
| Description: | 1 online resource (xvi, 375 pages) : illustrations (some color) |
| Language: | English |
| Series: | Methods in molecular biology, 1940-6029 ; volume no. 1414 Methods in molecular biology (Clifton, N.J.) ; v. 1414. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11254811 |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
|---|---|---|---|
| 001 | 11254811 | ||
| 006 | m o d | ||
| 007 | cr cn||||||||| | ||
| 008 | 160422s2016 nyua ob 001 0 eng d | ||
| 005 | 20250303141328.2 | ||
| 015 | |a GBB8M4822 |2 bnb | ||
| 016 | 7 | |a 101692208 |2 DNLM | |
| 016 | 7 | |a 019140360 |2 Uk | |
| 019 | |a 971084979 |a 974290013 |a 1005772302 |a 1079204594 | ||
| 020 | |a 9781493935697 |q (electronic bk.) | ||
| 020 | |a 1493935690 |q (electronic bk.) | ||
| 020 | |a 1493935674 | ||
| 020 | |a 9781493935673 | ||
| 020 | |z 9781493935673 |q (print) | ||
| 035 | 9 | |a (OCLCCM-CC)947120305 | |
| 035 | |a (OCoLC)947120305 |z (OCoLC)971084979 |z (OCoLC)974290013 |z (OCoLC)1005772302 |z (OCoLC)1079204594 | ||
| 037 | |a com.springer.onix.9781493935697 |b Springer Nature | ||
| 040 | |a RML |b eng |e rda |e pn |c RML |d RML |d OCLCO |d GW5XE |d TMC |d YDXCP |d COO |d SCB |d VT2 |d OCLCQ |d MERER |d OCLCO |d UAB |d OCLCO |d OTZ |d TFH |d OCLCO |d OCLCA |d BUF |d OCLCF |d OCLCO |d OCLCQ |d U3W |d OCLCO |d OCLCQ |d OCLCO |d OCLCQ |d OCLCO |d UKMGB |d OCLCA |d OCLCO |d OCLCQ |d OCL |d OCLCO | ||
| 049 | |a MAIN | ||
| 050 | 4 | |a QP551 | |
| 060 | 4 | |a QU 58.5 |b Q16 2016 | |
| 245 | 0 | 0 | |a Computational design of ligand binding proteins / |c edited by Barry L. Stoddard. |
| 264 | 1 | |a New York : |b Humana Press : |b Springer, |c ©2016. | |
| 300 | |a 1 online resource (xvi, 375 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Methods in molecular biology, |x 1940-6029 ; |v volume no. 1414 | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | 0 | |t In silico identification and characterization of protein-ligand binding sites / |r Daniel Barry Roche and Liam James McGuffin -- |t Computational modeling of small molecule ligand binding interactions and affinities / |r Marino Convertino and Nikolay V. Dokholyan -- |t Binding site prediction of proteins with organic compounds or peptides using GALAXY web servers / |r Lim Heo [and others] -- |t Rosetta and the Design of Ligand Binding Sites / |r Rocco Moretti [and others] -- |t PocketOptimizer and the design of ligand binding sites / |r Andre C. Stiel, Mehdi Nellen, and Birte Höcker -- |t Proteus and the design of ligand binding sites / |r Savvas Polydorides [and others] -- |t Structure-based design protocol for optimizing combinatorial protein libraries / |r Mark W. Lunt and Christopher D. Snow -- |t Combined and iterative use of computational design and directed evolution for protein-ligand binding design / |r Meng Wang and Huimin Zhao -- |t Improving binding affinity and selectivity of computationally designed ligand-binding proteins using experiments / |r Christine E. Tinberg and Sagar D. Khare -- |t Computational design of multinuclear metalloproteins using unnatural amino acids / |r William A. Hansen, Jeremy H. Mills, and Sagar D. Khare -- |t De novo design of metalloproteins and metalloenzymes in a three-helix bundle / |r Jefferson S. Plegaria and Vincent L. Pecoraro -- |t Design of light-controlled protein conformations and functions / |r Ryan S. Ritterson [and others] -- |t Computational Introduction of Catalytic Activity into Proteins / |r Steve J. Bertolani, Dylan Alexander Carlin, and Justin B. Siegel -- |t Generating high-accuracy peptide-binding data in high throughput with yeast surface display and SORTCERY / |r Lothar "Luther" Reich, Sanjib Dutta, and Amy E. Keating -- |t Design of specific peptide-protein recognition / |r Fan Zheng and Gevorg Grigoryan -- |t Computational design of DNA-binding proteins / |r Summer Thyme and Yifan Song -- |t Motif-driven design of protein-protein interfaces / |r Daniel-Adriano Silva, Bruno E. Correia, and Erik Procko -- |t Computational reprogramming of T cell antigen receptor binding properties / |r Timothy P. Riley [and others] -- |t Computational modeling of T cell receptor complexes / |r Timothy P. Riley [and others] -- |t Computational design of protein linkers / |r Brian Kuhlman, Tim Jacobs, and Tom Linskey -- |t Modeling of protein-RNA complex structures using computational docking methods / |r Bharat Madan [and others]. |
| 520 | |a This volume provides a collection of protocols and approaches for the creation of novel ligand binding proteins, compiled and described by many of today's leaders in the field of protein engineering. Chapters focus on modeling protein ligand binding sites, accurate modeling of protein-ligand conformational sampling, scoring of individual docked solutions, structure-based design program such as ROSETTA, protein engineering, and additional methodological approaches. Examples of applications include the design of metal-binding proteins and light-induced ligand binding proteins, the creation of binding proteins that also display catalytic activity, and the binding of larger peptide, protein, DNA and RNA ligands. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. | ||
| 650 | 0 | |a Proteomics |x Methodology. | |
| 650 | 0 | |a Protein binding. |0 http://id.loc.gov/authorities/subjects/sh85107654 | |
| 650 | 0 | |a Carrier proteins. |0 http://id.loc.gov/authorities/subjects/sh85020470 | |
| 650 | 0 | |a Ligands. |0 http://id.loc.gov/authorities/subjects/sh85076868 | |
| 650 | 0 | |a Protein engineering. |0 http://id.loc.gov/authorities/subjects/sh86007375 | |
| 650 | 1 | 2 | |a Ligands |
| 650 | 1 | 2 | |a Carrier Proteins |
| 650 | 2 | |a Protein Binding |0 https://id.nlm.nih.gov/mesh/D011485 | |
| 650 | 2 | 2 | |a Computational Biology |x methods |
| 650 | 2 | 2 | |a Computer Simulation |x statistics & numerical data |
| 650 | 2 | 2 | |a Protein Engineering |
| 650 | 6 | |a Protéomique |x Méthodologie. | |
| 650 | 6 | |a Protéines |x Fixation. | |
| 650 | 6 | |a Protéines de liaison. | |
| 650 | 6 | |a Ligands. | |
| 650 | 6 | |a Technologie des protéines. | |
| 650 | 7 | |a Proteins. |2 bicssc | |
| 650 | 7 | |a Science |x Life Sciences |x Biochemistry. |2 bisacsh | |
| 650 | 7 | |a Protein engineering |2 fast | |
| 650 | 7 | |a Carrier proteins |2 fast | |
| 650 | 7 | |a Ligands |2 fast | |
| 650 | 7 | |a Protein binding |2 fast | |
| 655 | 2 | |a Laboratory Manual | |
| 655 | 7 | |a Laboratory manuals |2 fast | |
| 655 | 7 | |a Laboratory manuals. |2 lcgft |0 http://id.loc.gov/authorities/genreForms/gf2014026120 | |
| 655 | 7 | |a Manuels de laboratoire. |2 rvmgf | |
| 700 | 1 | |a Stoddard, Barry L., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Computational design of ligand binding proteins. |d Totowa, N.J. : Humana Press, ©2016 |z 9781493935673 |
| 830 | 0 | |a Methods in molecular biology (Clifton, N.J.) ; |v v. 1414. |x 1064-3745 |0 http://id.loc.gov/authorities/names/n92002874 | |
| 856 | 4 | 0 | |u https://link.springer.com/10.1007/978-1-4939-3569-7 |y Springer Nature |
| 903 | |a HeVa | ||
| 929 | |a oclccm | ||
| 999 | f | f | |i c712ee7a-a109-5ff5-81c2-c71c5ad01948 |s a7813014-dc5f-57b6-b71a-a85cf2be39ef |
| 928 | |t Library of Congress classification |a QP551 |l Online |c UC-FullText |u https://link.springer.com/10.1007/978-1-4939-3569-7 |z Springer Nature |g ebooks |i 12536524 | ||