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|a SCI
|x 029000
|2 bisacsh
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100 |
1 |
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|a Smith, Moyra.
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245 |
1 |
0 |
|a Phenotypic variation :
|b exploration and functional genomics /
|c Moyra Smith.
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260 |
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|a Oxford ;
|a New York :
|b Oxford University Press,
|c 2011.
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300 |
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|a 1 online resource (xii, 240 pages) :
|b illustrations
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|b cr
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|a Includes bibliographical references (pages 200-227) and index.
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0 |
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|a Phenotype and functional genomics : introduction -- Evolution -- Genomic architecture and copy number changes -- Linkage, association, and linkage disequilibrium -- Regulation of transcription, splicing, and translation : impact of perturbation on phenotype -- Mitochondria : genome, functions, and phenotype -- Quality surveillance -- Neurodevelopment and functional genomics -- Neurobehavioral disorders -- Molecular analyses of malformation syndromes -- Multiple pathways including environmental factors that lead to a specific phenotype with later onset.
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|a Print version record.
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520 |
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|a During the past two decades international collaborative studies have yielded extensive information on genome sequences, genome architecture and their variations. The challenge we now face is to understand how these variations impact structure and function of organelles, physiological systems and phenotype. The goal of this book is to present steps in the pathways of exploration to connect genotype to phenotype and to consider how alterations in genomes impact disease. In this book the author reviews published research in functional genomics carried out primarily since 2006 that sheds light on.
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546 |
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|a English.
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650 |
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0 |
|a Phenotype.
|0 http://id.loc.gov/authorities/subjects/sh96012165
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650 |
|
0 |
|a Phenotypic plasticity.
|0 http://id.loc.gov/authorities/subjects/sh2006003746
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650 |
|
0 |
|a Genomics.
|0 http://id.loc.gov/authorities/subjects/sh2002000809
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650 |
1 |
2 |
|a Genetic Variation.
|
650 |
1 |
2 |
|a Phenotype.
|
650 |
2 |
2 |
|a Congenital Abnormalities
|x genetics.
|
650 |
2 |
2 |
|a Genomics.
|
650 |
2 |
2 |
|a Nervous System Diseases
|x genetics.
|
650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Genetics & Genomics.
|2 bisacsh
|
650 |
|
7 |
|a Genomics.
|2 fast
|0 (OCoLC)fst00940228
|
650 |
|
7 |
|a Phenotype.
|2 fast
|0 (OCoLC)fst01060531
|
650 |
|
7 |
|a Phenotypic plasticity.
|2 fast
|0 (OCoLC)fst01741023
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655 |
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0 |
|a Electronic books.
|
655 |
|
4 |
|a Electronic books.
|
776 |
0 |
8 |
|i Print version:
|a Smith, Moyra.
|t Phenotypic variation.
|d Oxford ; New York : Oxford University Press, 2011
|z 9780195379631
|w (DLC) 2010004048
|w (OCoLC)503614564
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|t Library of Congress classification
|a QH438.5 .S65 2011eb
|l Online
|c UC-FullText
|u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=e000xna&AN=368816
|z eBooks on EBSCOhost
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|i 12349816
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