Nanoscale materials in targeted drug delivery, theragnosis and tissue regeneration /

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Bibliographic Details
Imprint:Singapore : Springer, 2016.
Description:1 online resource (xix, 172 pages) : illustrations (some color)
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11263502
Hidden Bibliographic Details
Other authors / contributors:Yadav, Sudesh Kumar, editor.
ISBN:9789811008184
9811008183
9811008175
9789811008177
9789811008177
Digital file characteristics:text file PDF
Notes:Includes bibliographical references.
Online resource; title from PDF title page (SpringerLink, viewed June 13, 2016).
Summary:This book is the first of its kind to offer a comprehensive and up-to-date discussion of the use of nanoscale materials for biomedical applications, with a particular focus on drug delivery, theragnosis and tissue regeneration. It also describes in detail the methods used in the preparation of nanoparticles. Response of nanoparticles in biological systems are also explored. Nanotechnology has led to the advent of a new field, nanomedicine, which focuses on the use of nanomaterials as drug-delivery vehicles to develop highly selective and effective drugs. The combination of molecular imaging and nanotechnology has produced theragnostic nanoparticles, which allow the simultaneous detection and monitoring of diseases. Nanotechnology can also be combined with biomaterials to create scaffolds for tissue regeneration. Further, significant advances have been made in the areas of drug delivery, theragnostic nanoparticles and tissue regeneration materials. Some nanomedicines and tissue regeneration materials are already commercially available, while others are undergoing clinical trials, and promising results have been documented. Despite the rapid advances in nanomedicine, there is a relative dearth of literature on the biomedical applications of nanoscale materials.
Other form:Print version: Yadav, Sudesh Kumar. Nanoscale Materials in Targeted Drug Delivery, Theragnosis and Tissue Regeneration. Singapore : Springer Singapore, ©2016 9789811008177
Standard no.:10.1007/978-981-10-0818-4

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245 0 0 |a Nanoscale materials in targeted drug delivery, theragnosis and tissue regeneration /  |c Sudesh Kumar Yadav, editor. 
264 1 |a Singapore :  |b Springer,  |c 2016. 
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588 0 |a Online resource; title from PDF title page (SpringerLink, viewed June 13, 2016). 
505 0 |a Preface; Contents; About the Editor; Abbreviations; 1 Nanoscale Materials in Targeted Drug Delivery; Abstract; 1.1 Introduction; 1.2 Approaches for Synthesis of Nanoscale Materials; 1.3 Characterisation of Nanoscale Materials; 1.4 Types of Nanoscale Materials; 1.5 Targeted Drug Delivery; 1.6 Various Nanoscale Materials in Drug Delivery; 1.6.1 Polymeric Nanoparticles; 1.6.2 Metallic Nanoparticles; 1.6.3 Liposomes; 1.6.4 Quantum Dots; 1.6.5 Polymeric Micelles; 1.6.6 Carbon Nanotubes; 1.6.7 Dendrimers; 1.6.8 Magnetic Nanoparticles; 1.7 Conclusions; Acknowledgments 
505 8 |a 2 Biodegradable Nanoparticles and Their In Vivo FateAbstract; 2.1 Introduction; 2.2 Synthesis of Biodegradable Nanoparticles; 2.2.1 Synthesis of PLGA and PLA Nanoparticles; 2.2.2 Synthesis of Chitosan Nanoparticles; 2.2.3 Synthesis of Protein Nanoparticles; 2.3 Biodegradable Nanoparticles for Drug Delivery; 2.3.1 Biodegradable Nanoparticles for Delivery of Anticancer Drugs; 2.3.2 Biodegradable Nanoparticles for Delivery of Psychotic Drugs; 2.3.3 Biodegradable Nanoparticles for Delivery of Antimicrobial Drugs; 2.3.4 Biodegradable Nanoparticles for Delivery of Hepatoprotective Drugs 
505 8 |a 2.3.5 Biodegradable Nanoparticles for Proteins, Peptides and Nucleic Acids Delivery2.4 Drug Release Mechanisms from Biodegradable Nanoparticles; 2.5 Targeted Drug Delivery Using Biodegradable Nanoparticles; 2.6 Biological Barriers Encountered by Biodegradable NPs; 2.7 In Vivo Fate of Biodegradable Nanoparticles; 2.8 Toxicity of Biodegradable Nanoparticles; 2.9 Conclusions; Acknowledgments; References; 3 Metallic Nanoparticles, Toxicity Issues and Applications in Medicine; Abstract; 3.1 Introduction; 3.2 Physico-Chemical Properties of Metal and Metal Oxide NPs 
505 8 |a 3.3 Synthesis of Metal and Metal Oxide NPs3.3.1 Electrochemical Synthesis; 3.3.2 Sonochemical Method; 3.3.3 Thermal Decomposition; 3.3.4 Laser Ablation; 3.3.5 Chemical Reduction; 3.3.6 Polyol Method; 3.3.7 Microemulsion; 3.3.8 Biological Synthesis; 3.3.8.1 Bacteria-Mediated Synthesis; 3.3.8.2 Fungus-Mediated Synthesis; 3.3.8.3 Actinomycetes- and Yeast-Mediated Synthesis; 3.3.8.4 Plant-Mediated Synthesis; 3.4 Effect of Shape, Size and Surface Chemistry of NPs on Their Properties and Biological Behaviour; 3.5 Medical Prospects of Metallic Nanoparticles; 3.5.1 Disease Diagnostics 
505 8 |a 3.5.1.1 Imaging3.5.1.2 Cancer Detection; 3.5.2 Disease Therapy; 3.5.2.1 Anti-microbial Activity; 3.5.2.2 Cancer Treatment; 3.5.2.3 Treatment of Other Diseases; 3.5.2.4 Radiotherapy; 3.5.2.5 Gene Therapy; 3.5.2.6 Targeted Delivery and Controlled Drug Release; 3.5.3 Tissue Engineering; 3.5.4 Wound Healing and Skin Repair; 3.5.5 Theranostics; 3.6 Toxicity Issues Related to the Use of Nanomaterials; 3.7 Conclusions; Acknowledgements; References; 4 Liposomal and Phytosomal Formulations; Abstract; 4.1 Introduction; 4.2 Types of Liposomes; 4.2.1 Liposomes Based on Drug Delivery Systems 
520 |a This book is the first of its kind to offer a comprehensive and up-to-date discussion of the use of nanoscale materials for biomedical applications, with a particular focus on drug delivery, theragnosis and tissue regeneration. It also describes in detail the methods used in the preparation of nanoparticles. Response of nanoparticles in biological systems are also explored. Nanotechnology has led to the advent of a new field, nanomedicine, which focuses on the use of nanomaterials as drug-delivery vehicles to develop highly selective and effective drugs. The combination of molecular imaging and nanotechnology has produced theragnostic nanoparticles, which allow the simultaneous detection and monitoring of diseases. Nanotechnology can also be combined with biomaterials to create scaffolds for tissue regeneration. Further, significant advances have been made in the areas of drug delivery, theragnostic nanoparticles and tissue regeneration materials. Some nanomedicines and tissue regeneration materials are already commercially available, while others are undergoing clinical trials, and promising results have been documented. Despite the rapid advances in nanomedicine, there is a relative dearth of literature on the biomedical applications of nanoscale materials. 
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