Progress in the chemistry of organic natural products. Volume 102 /
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| Imprint: | Switzerland : Springer, 2016. |
|---|---|
| Description: | 1 online resource (v, 252 pages) : illustrations |
| Language: | English |
| Series: | Progress in the chemistry of organic natural products, 2191-7043 ; 102 Progress in the chemistry of organic natural products (2011) ; 102. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11264556 |
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| 245 | 0 | 0 | |a Progress in the chemistry of organic natural products. |n Volume 102 / |c A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, editors ; with contributions by G. Appendino [and 3 others]. |
| 264 | 1 | |a Switzerland : |b Springer, |c 2016. | |
| 300 | |a 1 online resource (v, 252 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
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| 490 | 1 | |a Progress in the chemistry of organic natural products, |x 2191-7043 ; |v 102 | |
| 588 | 0 | |a Online resource; title from PDF title page (SpringerLink, viewed July 13, 2016). | |
| 504 | |a Includes bibliographical references. | ||
| 505 | 0 | |a The Laurencia paradox:an endless source of chemodiversity. -- Ingenane Dipernoids. | |
| 520 | |a The first contribution reviews the phytochemical, chemical, and biological literature on members of the ingenane class of diterpenoids from their first isolation in 1968 through 2015, highlighting unresolved issues both common to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the light of the Jakupovic proposal of a dissection between the formation of the macrocyclic Euphorbia diterpenoids and the phorboids, and the clinical development of ingenol mebutate is chronicled in the light of its "reverse-pharmacology" focus. The second contribution offers a comprehensive view of the chemical wealth and the taxonomic problems currently impeding chemical and biological investigations of the genus Laurencia. It addresses the botanical description and the growth and population dynamics of the genus, as well as its chemical diversity and ecological relations; the secondary metabolites as well as their sources of isolation; and finally the biological activity. | ||
| 650 | 0 | |a Chemistry, Organic. |0 http://id.loc.gov/authorities/subjects/sh85023022 | |
| 650 | 0 | |a Natural products. |0 http://id.loc.gov/authorities/subjects/sh85090252 | |
| 650 | 7 | |a SCIENCE |x Chemistry |x Organic. |2 bisacsh | |
| 650 | 7 | |a Natural products. |2 fast |0 (OCoLC)fst01034390 | |
| 650 | 7 | |a Chemistry. |2 fast |0 (OCoLC)fst00853344 | |
| 650 | 7 | |a Chemistry, Organic. |2 fast |0 (OCoLC)fst00853501 | |
| 650 | 7 | |a Clinical biochemistry. |2 fast |0 (OCoLC)fst00864329 | |
| 650 | 7 | |a Pharmaceutical chemistry. |2 fast |0 (OCoLC)fst01060115 | |
| 655 | 0 | |a Electronic books. | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Kinghorn, A. Douglas, |e editor. |0 http://id.loc.gov/authorities/names/n79070822 | |
| 700 | 1 | |a Falk, Heinz, |d 1939- |e editor. |0 http://id.loc.gov/authorities/names/n78015838 | |
| 700 | 1 | |a Gibbons, Simon, |e editor. |0 http://id.loc.gov/authorities/names/no2014020801 | |
| 700 | 1 | |a Kobayashi, Jun'ichi, |e editor. |0 http://id.loc.gov/authorities/names/nb2016004029 | |
| 776 | 0 | 8 | |i Print version: |t Progress in the chemistry of organic natural products. Volume 102. |d Cham : Springer, [2016] |z 9783319331706 |w (OCoLC)945745191 |
| 830 | 0 | |a Progress in the chemistry of organic natural products (2011) ; |v 102. |0 http://id.loc.gov/authorities/names/no2013045301 | |
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