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|a Evolution of the protein synthesis machinery and its regulation /
|c Greco Hernández, Rosemary Jagus, editors.
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| 264 |
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1 |
|a Switzerland :
|b Springer,
|c 2016.
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| 300 |
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|a 1 online resource (ix, 564 pages) :
|b illustrations (some color)
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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|a online resource
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| 347 |
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|a text file
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|b PDF
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|a Preface; Contents; 1 Evolution of tRNAs Was Driven by Entropic Forces; 1 Introduction; 1.1 The tRNA Code; 1.2 tRNA Genes; 2 Entropy in tRNA Molecules; 3 Conclusions; Acknowledgments; References; 2 The Phylogenomic Roots of Translation; 1 Introduction; 2 A Structural Phylogenomic Method to Study the Evolution of Macromolecules; 3 The Early Emergence of Proteins and Metabolism; 4 Insights into the Generation of the First Protein Structures; 5 Late Evolutionary Appearance of First Structural Domains Interacting with RNA; 6 The Co-evolutionary History of Emerging tRNA, Ribosomes and Proteins
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8 |
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|a 7 tRNAs Are Evolutionary Building Blocks of Ribosomes and Genomes8 Conclusions; Acknowledgments; References; 3 Origins and Early Evolution of the Ribosome; 1 The Beginnings: Origins of the PTC and Possible Existence of an RNA World; 1.1 Background; 1.2 RNA World; 1.3 Peptidyl Transferase Center; 2 Toward a Timeline for the Subsequent Evolution of the Translation Machinery; 2.1 Initial Models of Ribosomal RNA Age; 2.2 Accretion Model for Ribosomal RNA History; 2.3 Is the PTC the Oldest Portion of the Ribosome?; 3 Major Events Along the Timeline; 3.1 Homochirality and the Ribosome
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| 505 |
8 |
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|a 3.2 tRNA and the Timeline3.3 Ribosome History Has Implications for the Origin of the Genetic Code; 3.4 Ribosomal Proteins Line the Path to Increasing Complexity; 3.5 Origins of the Dynamic Ribosome; 3.6 Recent Aspects of Ribosome Evolution; 3.6.1 Trigger Factor and Factor Binding Site; 3.6.2 5S rRNA; 4 Summary and Future Studies; References; 4 Evolution of Translational Initiation: From Archaea to Eukarya; 1 Translation Initiation: An Evolutionary Overview; 2 mRNA Features in the Three Domains of Life; 3 Translation Initiation Factors: Conservation and Divergence in the Three Domains of Life
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|a 3.1 Universally Conserved TIFs3.2 The Archaeal/Eukaryal Factors; 3.2.1 a/eIF2; 3.2.2 a/eIF6; 4 Conclusions: The Early Evolution of the Translation Initiation Machinery; References; 5 On the Origin and Early Evolution of Translation in Eukaryotes; 1 Introduction; 2 Translation Initiation in the Prokaryotic World; 2.1 mRNA Recruitment in the Last Universal Common Ancestor of Extant Organisms; 3 Translation Initiation in Modern Eukaryotes; 4 The Emergence of Eukaryotic Translation; 4.1 A Closer Look at the Untranslated Regions of Eukaryotic mRNAs
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|a 5 The Transition from Prokaryotic to Eukaryotic Translation5.1 What Was the Mechanism of mRNA Recruiting in the Early Eukaryotes?; 6 The Natural History of the Cap Structure, eIF4s and PABP Sheds Light on the Evolution of the Cap-Dependent Translation; 6.1 Origin of the Cap Structure of mRNAs; 6.2 Origin of Eukaryotic Initiation Factors 3, 4G and 4E; 6.3 Origin of PABP and the Evolution of mRNA Circularization; 6.4 Origin of eIF4A and the Evolution of the Scanning Process; 7 A Timeline for the Emergence of the Cap-Dependent Translation Initiation; 8 Concluding Remarks; Acknowledgments
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| 588 |
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|a Online resource; title from PDF title page (SpringerLink, viewed August 24, 2016).
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| 520 |
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|a The "omics" era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.
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|a Includes bibliographical references at the end of each chapters.
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| 650 |
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0 |
|a Proteins
|x Synthesis.
|0 http://id.loc.gov/authorities/subjects/sh85107655
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| 650 |
1 |
2 |
|a Protein Biosynthesis.
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| 650 |
|
7 |
|a Evolution.
|2 bicssc
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| 650 |
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7 |
|a Cellular biology (cytology)
|2 bicssc
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| 650 |
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7 |
|a Botany & plant sciences.
|2 bicssc
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| 650 |
|
7 |
|a Zoology & animal sciences.
|2 bicssc
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| 650 |
|
7 |
|a Proteins.
|2 bicssc
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| 650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Biochemistry.
|2 bisacsh
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| 650 |
|
7 |
|a Proteins
|x Synthesis.
|2 fast
|0 (OCoLC)fst01079764
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| 655 |
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4 |
|a Electronic books.
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| 700 |
1 |
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|a Hernández, Greco,
|e editor.
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| 700 |
1 |
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|a Jagus, Rosemary,
|e editor.
|
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|t Library of Congress classification
|a QP551
|l Online
|c UC-FullText
|u https://link.springer.com/10.1007/978-3-319-39468-8
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|i 12539230
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