New therapeutics for traumatic brain injury : prevention of secondary brain damage and enhancement of repair and regeneration /
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Imprint: | London : Academic Press is an imprint of Elsevier, [2017] ©2017 |
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Description: | 1 online resource (xxv, 325 pages) : illustrations (some color) |
Language: | English |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11267184 |
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245 | 0 | 0 | |a New therapeutics for traumatic brain injury : |b prevention of secondary brain damage and enhancement of repair and regeneration / |c edited by Kim A. Heidenreich. |
264 | 1 | |a London : |b Academic Press is an imprint of Elsevier, |c [2017] | |
264 | 4 | |c ©2017 | |
300 | |a 1 online resource (xxv, 325 pages) : |b illustrations (some color) | ||
336 | |a text |b txt |2 rdacontent |0 http://id.loc.gov/vocabulary/contentTypes/txt | ||
337 | |a computer |b c |2 rdamedia |0 http://id.loc.gov/vocabulary/mediaTypes/c | ||
338 | |a online resource |b cr |2 rdacarrier |0 http://id.loc.gov/vocabulary/carriers/cr | ||
504 | |a Includes bibliographical references and index. | ||
505 | 0 | 0 | |t Part I: Interventional therapies for TBI previously or currently in phase 3 clinical trials. Why did the phase III clinical trials for progesterone in TBI fail? An analysis of three potentially critical factors / |r D.G. Stein, R.B. Howard, I. Sayeed -- |t Hypothermia for traumatic brain injury: current evidence and future directions / |r H. Mtaweh, D. Simon, M.J. Bell -- |t The future of TBI: hyperbaric oxygen as a primary therapeutic approach / |r B. Miskin, L.A. Fox -- |t Part II: Repurposing FDA approved drugs for TBI treatment. Erythropoietin and its derivatives: mechanisms of neuroprotection and challenges in clinical translation / |r T. Bogoslovsky, J.D. Bernstock, K. Kenney, C. Moore, R. Diaz-Arrastia -- |t Atorvastatin in the treatment of traumatic brain injury / |r A.N. Sen, S.P. Gopinath, C.S. Robertson -- |t The application of glibenclamide in traumatic brain injury / |r D.S. Hersh, J.M. Simard, H.M. Eisenberg -- |t Perispinal etanercept for traumatic brain injury / |r E. Tobinick, H. Rodriguez-Romanacce, R. Kinssies, N. Kim -- |t Part III: Interventional drugs for TBI in phase 1-2 clinical trials. Nitric oxide synthase inhibitors in traumatic brain injury / |r R. Schinzel, F. Tegtmeier -- |t Management of paroxysmal sympathetic hyperactivity after traumatic brain injury / |r L.D. Wilson, T.C. Leath, M.B. Patel -- |t Part IV: Interventional drugs for TBI in preclinical development. The use of estrogen for the treatment of traumatic brain injury / |r W.J. Hubbard, I.H. Chaudry -- |t Voltage-gated calcium channel blockers for the treatment of traumatic brain injury / |r G.G. Gurkoff, K. Shahlaie, B.G. Lyeth, R.F. Berman -- |t 5-lipoxygenase-activating protein inhibitors: promising drugs for treating acute and chronic neuroinflammation following brain injury / |r K.A. Heidenreich, C.E. Corser-Jensen -- |t Carbonyl scavenging as an antioxidant neuroprotective strategy for acute traumatic brain injury / |r J.E. Cebak, I.N. Singh, J.A. Wang, R.L. Hill, J.R. Kulbe, E.D. Hall -- |t TrkB receptor agonist 7,8-Dihydroxyflavone and its therapeutic potential for traumatic brain injury / |r J. Romeika, M. Wurzelmann, D. Sun -- |t Ceftriaxone treatment of TBI / |r M.Q. Hameed, A. Rotenberg -- |t Part V: Drugs for TBI rehabilitation. Memantine: a safe and tolerable NMDA antagonist with potential benefits in traumatic brain injury / |r M.A. Keiski -- |t Interventional drugs for TBI Rehabilitation of cognitive impairment: the cholinesterase inhibitor rivastigmine / |r M.A. Hernandez-Tejada, O. Brawman-Mintzer -- |t Docosahexaenoic acid and omega 3 fatty acids / |r M.E. Schober -- |t Treatment of mood disorders following traumatic brain injury / |r H.L. Lin, R.E. Jorge |
520 | |a "New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury"--Publisher's description. | ||
588 | 0 | |a Online resource; title from electronic title page (ScienceDirect viewed March 27, 2018). | |
650 | 0 | |a Brain damage |x Treatment. | |
650 | 0 | |a Brain damage |x Rehabilitation. | |
650 | 0 | |a Brain |x Wounds and injuries |x Complications. |0 http://id.loc.gov/authorities/subjects/sh85016355 | |
650 | 7 | |a Brain damage |x Treatment. |2 fast |0 http://id.worldcat.org/fast/fst00837745 | |
650 | 7 | |a Brain |x Wounds and injuries |x Complications. |2 fast |0 http://id.worldcat.org/fast/fst00837695 | |
650 | 7 | |a MEDICAL / Neurology |2 bisacsh | |
650 | 7 | |a Brain damage |x Rehabilitation. |2 fast |0 http://id.worldcat.org/fast/fst00837740 | |
650 | 1 | 2 | |a Brain Injuries, Traumatic |x drug therapy. |0 http://id.nlm.nih.gov/mesh/D000070642Q000188 |
650 | 1 | 2 | |a Brain Injuries, Traumatic |x complications. |0 http://id.nlm.nih.gov/mesh/D000070642Q000150 |
650 | 2 | 2 | |a Brain |x drug effects. |0 http://id.nlm.nih.gov/mesh/D001921Q000187 |
650 | 2 | 2 | |a Clinical Trials as Topic. |0 http://id.nlm.nih.gov/mesh/D002986 |
655 | 4 | |a Electronic books. | |
700 | 1 | |a Heidenreich, Kim A., |e editor. |0 http://id.loc.gov/authorities/names/n2017181976 | |
776 | 0 | 8 | |i Print version: |t New therapeutics for traumatic brain injury. |d Amsterdam ; Boston : Elsevier/Academic Press, [2017] |z 9780128026861 |w (DLC) 2016942110 |w (OCoLC)971597802 |
903 | |a HeVa | ||
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928 | |t Library of Congress classification |a RC387.5 |l Online |c UC-FullText |u https://www.sciencedirect.com/science/book/9780128026861 |z Elsevier |g ebooks |i 10979562 |