Fish vaccines /

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Bibliographic Details
Imprint:Basel : Springer, ©2016.
Description:1 online resource (v, 180 pages) : color illustrations
Language:English
Series:Birkhäuser advances in infectious diseases
Birkhäuser advances in infectious diseases.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11268036
Hidden Bibliographic Details
ISBN:9783034809801
3034809808
9783034809788
3034809786
Digital file characteristics:text file PDF
Notes:Includes index.
Includes bibliographical references at the end of each chapters and index.
Online resource; title from PDF title page (EBSCO, viewed November 8, 2016).
Summary:This book provides a useful text for research students and scientists on the latest knowledge about the immune system of fish, cutting edge technologies and the step required to develop, test and commercialise fish vaccines. It brings together information that is currently difficult to obtain in one book, and highlights problem areas and research topics that still need to be addressed to improve future vaccines.
Other form:Printed edition: 9783034809788
Standard no.:10.1007/978-3-0348-0980-1
10.1007/978-3-0348-0
Table of Contents:
  • Chapter 1: Fish Disease Causing Economic Impact in€Global Aquaculture; Introduction; Salmonids; Viral Diseases of€Salmonids; Bacterial Diseases of€Salmonids; Parasitic Diseases of€Salmonids; Carp; Viral Diseases of€Carp; Bacterial Diseases of€Carp; Fungal Diseases of€Carp; Bacterial and€Viral Diseases in€Tilapia; Bacterial and€Viral Diseases in€Catfish; Parasitic Disease in€Catfish; Marine Fish Aquaculture; Viral Disease in€Marine Finfish; Bacterial and€Parasitic Disease in€Marine Fish; Conclusions; References; Chapter 2: Overview of€the€Fish Adaptive Immune System.
  • Introduction MHC Class I€and€Class II Molecules; T-Cell Receptors; T-Helper Cell-Associated Cytokines; Cytotoxic T Cells and€Antiviral Immunity; Helper T-Cell Activation and€Memory; B-Cell Activation; B-Cell Maturation; Immunoglobulins (Ig) and€B-Cell Populations; Memory B Cells; Markers of€Protection; Conclusions; References; Chapter 3: Development of€Fish Vaccines: Focusing on€Methods; Introduction; Immunological Basis; Immunity and€Vaccination of€Fish; The Start; Current Vaccines in€Different Markets; Development Trends; Modalities: Mucosal Vaccines.
  • Modalities: Injection Vaccines Modalities and€Fish Size; Non-replicating or Nonlive Vaccines; Adjuvants and€Principle of€Action; Immunomodulation; Molecular Technologies; Recombinant Vaccines; Subunit Vaccines; Genetically Modified Vaccines; Vector Vaccines; DNA Vaccines; Marker Vaccines; Vaccines Against Parasitic Diseases; Future Directions; References; Chapter 4: Adjuvants and€Delivery Methods: Current and€Novel; Introduction; Principles of€How Adjuvants Work; Signal 1 Adjuvants Used in€Fish Vaccinology; Freund's Complete Adjuvant; Freund's Incomplete Adjuvant; Montanide.
  • Other Mineral Oil Adjuvants Signal 2 Facilitators and€TLR Ligands as€Adjuvants or Immunostimulants; Aluminium-Containing Adjuvants; ß-Glucans; Saponins; Poly I:C; Lipopeptides; Flagellins; Synthetic Oligodeoxynucleotides; Cytokines; Immersion Delivery of€Fish Vaccines; Novel Strategies for€Oral Vaccination; Microparticles/Nanoparticles; PLGA Particles; ISCOMs; Alginate; Chitosan; Alternative Methods for€Oral Delivery; Conclusive Remarks and€Perspectives; References.
  • Chapter 5: Fish Vaccines: The€Regulatory Process and€Requirements from€the€Laboratory Bench to€a€Final Commercial Product, Including Field Trials Introduction; Vaccine Types; Antigen Development; Vaccine Development Process; In-Process Testing; Assay Development and€Validation; Formulation/Blending of€Bulk Vaccine; Selection of€Final Containers; Development Testing/Preregistration Testing; Final Product Testing; Batch Consistency; Stability; Compiling the€Registration Dossier; The Application for€a€Marketing Authorisation; Manufacturing Standards.