Fundamentals of pediatric drug dosing /
Saved in:
Imprint: | Switzerland : Adis, [2016] ©2016 |
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Description: | 1 online resource (viii, 146 pages) : illustrations (some color) |
Language: | English |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11268646 |
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245 | 0 | 0 | |a Fundamentals of pediatric drug dosing / |c Iftekhar Mahmood, Gilbert Burckart, editors. |
264 | 1 | |a Switzerland : |b Adis, |c [2016] | |
264 | 4 | |c ©2016 | |
300 | |a 1 online resource (viii, 146 pages) : |b illustrations (some color) | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
347 | |a text file |b PDF |2 rda | ||
504 | |a Includes bibliographical references. | ||
505 | 0 | 0 | |g 1. |t Pediatric Drug Development and the Regulatory Changes That Are Creating the Science of Pediatric Dosing / |r Gilbert J. Burckart -- |g 2. |t Pediatric Physiology / |r Iftekhar Mahmood -- |g 3. |t Developmental Pharmacology: Impact on Pharmacokinetics and Pharmacodynamics -- of Drugs / |r Iftekhar Mahmood -- |g 4. |t Pediatric Clinical Trial Design and Dosing / |r Dionna Green and Valerie Amspacher -- |g 5. |t Application of Allometric Principles in Pediatric Drug Development / |r Iftekhar Mahmood -- |g 6. |t Population Pharmacokinetics in Pediatric Drug Development / |r Jeremiah D. Momper, John Bradley, and Brookie M. Best -- |g 7. |t Scaling Dose-Exposure-Response from Adults to Children / |r Ine Skottheim Rusten, Anna Nordmark, Susan Cole, Joseph F. Standing, Sofi a Friberg Hietala, Wei Zhao, Valeria Gigante, Anna Karin Hamberg, Gérard Pons, María Jesús Garrido, Johannes Taminiau, Norbert Benda, Frederike Lentz, Flora Musuamba Tshinanu, Andrew Thomson, Paolo Tomasi, Cecile Ollivier, Ralf Herold, and Efthymios Manolis -- |g 8. |t Applications of Physiologically Based Pharmacokinetic (PBPK) Models for Pediatric Populations / |r Peng Duan, Jeffrey Fisher, and Jian Wang -- |g 9. |t Perinatal Pharmacology and Maternal/Fetal Dosing / |r Iftekhar Mahmood, Gilbert J. Burckart and Robert M. Ward. |
520 | |a "Focused on pediatric physiology, pharmacology, pharmacokinetics and pharmacodynamics, this book illustrates the differences between the pediatric population and adults; knowledge of extreme importance not only during pediatric drug development but also in the clinical practice. Physicians, nurses, clinical pharmacologists, researchers and healthcare professionals will find this an invaluable resource. With the advent of pediatric exclusivity, and requirements to conduct clinical studies in children, an emphasis has been placed on finding a safe and efficacious dose of a drug in children. Children are not 'small adults', and drug dosing in this population requires special consideration. There are subtle physiological and biochemical differences among neonates, infants, children, adolescents and adults and dosing in pediatrics requires proper understanding of these factors. Furthermore, dosing in children, as in adults, should be based on pharmacokinetic and pharmacodynamic data. This is an evolving area, as pediatric pharmacokinetic studies are becoming mandatory for getting approval of new drugs in this population."--Publisher's description. | ||
588 | 0 | |a Online resource; title from PDF title page (SpringerLink, viewed November 7, 2016). | |
650 | 0 | |a Drugs |x Dosage. | |
650 | 0 | |a Pediatric pharmacology. |0 http://id.loc.gov/authorities/subjects/sh85099170 | |
650 | 2 | |a Pharmaceutical Preparations |x administration & dosage. | |
650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
650 | 7 | |a Drugs |x Dosage. |2 fast |0 (OCoLC)fst01432036 | |
650 | 7 | |a Pediatric pharmacology. |2 fast |0 (OCoLC)fst01056473 | |
655 | 0 | |a Electronic books. | |
655 | 4 | |a Electronic books. | |
700 | 1 | |a Mahmood, Iftekhar |c (Clinical pharmacologist), |e editor. |4 edt |0 http://id.loc.gov/authorities/names/no2004072082 | |
700 | 1 | |a Burckart, Gilbert J., |e editor |4 edt | |
776 | 0 | 8 | |i Print version: |t Fundamentals of pediatric drug dosing. |d Switzerland : Adis, 2016 |z 9783319437521 |w (DLC) 2016956626 |w (OCoLC)952788819 |
903 | |a HeVa | ||
929 | |a oclccm | ||
999 | f | f | |i f1e0f49c-d6c6-5e8b-8509-d009043279bd |s bacad002-015f-538d-9d6b-29759d7d9893 |
928 | |t Library of Congress classification |a RM138 .F859 2016 |l Online |c UC-FullText |u https://link.springer.com/10.1007/978-3-319-43754-5 |z Springer Nature |g ebooks |i 12541348 |