Breast cancer survivorship : consequences of early breast cancer and its treatment /
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Imprint: | Cham, Switzerland : Springer, 2016. |
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Description: | 1 online resource : illustrations |
Language: | English |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11269796 |
Table of Contents:
- Foreword; Preface; References; Acknowledgments; Contents; Contributors; Chapter 1: Introduction; Breast Cancer Incidence and Mortality; Prevalence of Breast Cancer Survivors; Population Characteristics of Breast Cancer Survivors; Tumor Characteristics; Breast Cancer Stage; Breast Cancer Biology; Treatment Overview for Early Breast Cancer; Surgery; Adjuvant Chemotherapy; Adjuvant Trastuzumab (Herceptin®); Adjuvant Radiotherapy; Adjuvant Endocrine Therapy; Summary; References; Part I: Disease Recurrence; Chapter 2: Predicting Risk of Disease Recurrence; Introduction.
- What Does Recurrence Mean? What Are the Risks of Recurrence?; Why Do We Need to Better Identify the Risk of Recurrence?; How Can We Identify Those at Highest Risk?; Intrinsic Subtypes; Prognostic Versus Predictive Tests; Non-molecular Decision Aids; Nottingham Prognostic Index; Adjuvant! Online; Predict; The IHC4 + C Score; Commercially Available Molecular Assays; Recurrence Score; Prosigna® ROR; Endopredict®; Mammaprint; Breast Cancer Index; Other Biomarkers for Predicting Risk of Recurrence; What Are the Timeframes for Relapse?; What Are the Patterns of Relapse?
- ConclusionReferences; Chapter 3: Detection of Recurrence: Clinical Follow-Up; Guidelines; Clinical Examination and Routine Appointments; Identification of Early Secondary Disease; Models of Follow Up Care; Potential Model for Patient-Led Care; Conclusion; References; Chapter 4: Detection of Recurrence: Imaging Strategies; Introduction; Current Imaging Modalities Used in Breast Cancer Survivors; Mammography; Magnetic Resonance Imaging and Ultrasound; Mammographically Occult Tumors; Imaging the Post Mastectomy Breast; Higher Risk Groups; Staging in Recurrent Disease.
- Future Directions Tomosynthesis; Oligometastatic Disease; Risk Stratified Surveillance; Conclusion; References; Chapter 5: Follow Up of Patients with Germline Mutations in High Risk Predisposition Genes; The Genetic Architecture of Breast Cancer Susceptibility; Rare, High-Penetrance Predisposition Genes; Rare, Moderate-Penetrance Predisposition Genes; Common, Low-Penetrance Predisposition Genes; Clinical Utility; Germline BRCA1 and BRCA2 Mutations and Risks of Cancer; Contralateral Breast Cancer in BRCA Carriers; Risk of Contralateral Breast Disease in BRCA Carriers.
- Impact of Contralateral Prophylactic Mastectomy Breast Screening in BRCA Carriers; Ovarian Cancer in BRCA Carriers; Ovarian Screening; Risk Reducing Bilateral Salpingo-Oophorectomy; Impact of Oophorectomy After Breast Cancer Diagnosis; Other High-Risk Predisposition Genes; Implications for Family Members; Fertility and Preimplantation Genetic Diagnosis (PGD); Cascade Testing; The Future; References; Part II: Interventions to Reduce Risk of Recurrence; Chapter 6: Endocrine Therapy; Introduction; Endocrine Therapy for the First 5 Years; Tamoxifen.