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|a The innate immune system :
|b a compositional and functional perspective /
|c Tom P. Monie.
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|a London, United Kingdom :
|b Academic Press,
|c 2017.
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|a Front Cover; The Innate Immune System; Dedication; The Innate Immune System: A compositional and functional perspective; Copyright; Contents; Preface; Acknowledgments; 1 -- A Snapshot of the Innate Immune System; 1.1 A BRIEF HISTORY OF IMMUNITY; 1.1.1 The Rise of Innate Immunity; 1.1.2 Self, Nonself, and the "Danger" Hypothesis; 1.2 THE IMMUNE SYSTEM-A COMPLEX DEFENSE SYSTEM; 1.3 FUNCTIONAL ELEMENTS ON THE INNATE IMMUNE RESPONSE; 1.3.1 Barrier Functions; 1.3.2 Immune Tissues; 1.3.3 Immune Cells; 1.3.3.1 Granulocytes; 1.3.3.2 Monocytes; 1.3.3.3 Antigen-Presenting Cells.
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| 505 |
8 |
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|a 1.3.3.4 Lymphocytes and Natural Killer Cells1.3.4 Protein and Peptide Defenses; 1.3.4.1 Pattern Recognition; 1.3.4.2 Complement; 1.3.4.3 Cytokines; 1.3.5 Cell Death; 1.4 THE MUCOSA-ASSOCIATED INNATE IMMUNE SYSTEM; 1.4.1 The Cells of the Gastrointestinal Tract Epithelium and Their Role in Innate Defense Mechanisms; 1.4.2 Peyer's Patches and M Cells; 1.4.3 Secreted Defenses; 1.4.3.1 Antimicrobial Peptides; 1.4.3.2 Immunoglobulin A; 1.4.3.3 Commensal Flora; 1.5 ADDITIONAL HOMEOSTATIC FUNCTIONS INVOLVED IN INNATE IMMUNE RESPONSES; 1.5.1 The Heat Shock Response; 1.5.2 The Unfolded Protein Response.
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| 505 |
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|a 1.5.3 AutophagyREFERENCES AND FURTHER READING; Sections 1.1. and 1.2; Section 1.3; Section 1.4; Section 1.5; 2 -- Immune Cells and the Process of Pattern Recognition; 2.1 THE CELLULAR BASIS OF THE INNATE IMMUNE SYSTEM; 2.1.1 Monocytes; 2.1.2 Macrophages; 2.1.2.1 The Brain; 2.1.2.2 The Spleen; 2.1.2.3 The Bones; 2.1.2.4 The Lungs; 2.1.2.5 The Liver; 2.1.3 Dendritic Cells; 2.1.4 Neutrophils; 2.1.4.1 Migration From the Circulation; 2.1.4.2 Neutrophil-Driven Bacterial Killing; 2.1.5 Eosinophils; 2.1.6 Mast Cells and Basophils; 2.1.7 Innate Lymphoid Cells; 2.1.7.1 Natural Killer Cells.
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| 505 |
8 |
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|a 2.2.4.2 Dectin-2 and Mincle2.2.4.3 Tyrosine-Based Activation Motif-Independent Signaling by C-Type Lectin Receptorss; 2.2.4.4 C-Type Lectin Receptors Can Act as Inhibitory Receptors; 2.2.5 Cytoplasmic Pattern Recognition Receptors; 2.2.6 Nucleotide-Binding, Leucine-Rich Repeat-Containing Receptor Signaling; 2.2.6.1 NOD1 and NOD2 Receptor Signaling; 2.2.6.2 Inflammasome-Based Signaling; 2.2.7 Nucleic Acid-Sensing Immune Receptors in the Cytoplasm; 2.2.7.1 The RIG-I Family; 2.2.7.2 The PYHIN Receptor Family; 2.2.7.3 STING and the Innate Detection of Nucleic Acids; REFERENCES AND FURTHER READING.
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| 506 |
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|a Owing to Legal Deposit regulations this resource may only be accessed from within National Library of Scotland. For more information contact enquiries@nls.uk.
|5 StEdNL
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|a Natural immunity.
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|a Natural immunity.
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|a Monie, Tom.
|t Innate immune system.
|d London, United Kingdom : Academic Press, 2017
|z 0128044640
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|a 2.1.7.2 Type I Innate Lymphoid Cells2.1.7.3 Type II Innate Lymphoid Cells; 2.1.7.4 Type III Innate Lymphoid Cells; 2.1.8 Gamma-Delta (γδ) T Cells; 2.2 PATTERN RECOGNITION RECEPTOR SIGNALING PATHWAYS; 2.2.1 Pattern Recognition Receptors Recognize Exogenous and Endogenous Dangers; 2.2.2 Domain Organization of the Pattern Recognition Receptors; 2.2.3 Toll-Like Receptor Signaling; 2.2.3.1 Toll-Like Receptors at the Plasma and Endosomal Membrane; 2.2.3.2 Toll-Like Receptor Signaling Pathways; 2.2.3.2.1 The Myddosome Complex; 2.2.4 C-Type Lectin Receptor Signaling; 2.2.4.1 Dectin-1.
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