The innate immune system : a compositional and functional perspective /
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| Author / Creator: | Monie, Tom. |
|---|---|
| Imprint: | London, United Kingdom : Academic Press, 2017. |
| Description: | 1 online resource (230) |
| Language: | English |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11271922 |
Table of Contents:
- Front Cover; The Innate Immune System; Dedication; The Innate Immune System: A compositional and functional perspective; Copyright; Contents; Preface; Acknowledgments; 1
- A Snapshot of the Innate Immune System; 1.1 A BRIEF HISTORY OF IMMUNITY; 1.1.1 The Rise of Innate Immunity; 1.1.2 Self, Nonself, and the "Danger" Hypothesis; 1.2 THE IMMUNE SYSTEM-A COMPLEX DEFENSE SYSTEM; 1.3 FUNCTIONAL ELEMENTS ON THE INNATE IMMUNE RESPONSE; 1.3.1 Barrier Functions; 1.3.2 Immune Tissues; 1.3.3 Immune Cells; 1.3.3.1 Granulocytes; 1.3.3.2 Monocytes; 1.3.3.3 Antigen-Presenting Cells.
- 1.3.3.4 Lymphocytes and Natural Killer Cells1.3.4 Protein and Peptide Defenses; 1.3.4.1 Pattern Recognition; 1.3.4.2 Complement; 1.3.4.3 Cytokines; 1.3.5 Cell Death; 1.4 THE MUCOSA-ASSOCIATED INNATE IMMUNE SYSTEM; 1.4.1 The Cells of the Gastrointestinal Tract Epithelium and Their Role in Innate Defense Mechanisms; 1.4.2 Peyer's Patches and M Cells; 1.4.3 Secreted Defenses; 1.4.3.1 Antimicrobial Peptides; 1.4.3.2 Immunoglobulin A; 1.4.3.3 Commensal Flora; 1.5 ADDITIONAL HOMEOSTATIC FUNCTIONS INVOLVED IN INNATE IMMUNE RESPONSES; 1.5.1 The Heat Shock Response; 1.5.2 The Unfolded Protein Response.
- 1.5.3 AutophagyREFERENCES AND FURTHER READING; Sections 1.1. and 1.2; Section 1.3; Section 1.4; Section 1.5; 2
- Immune Cells and the Process of Pattern Recognition; 2.1 THE CELLULAR BASIS OF THE INNATE IMMUNE SYSTEM; 2.1.1 Monocytes; 2.1.2 Macrophages; 2.1.2.1 The Brain; 2.1.2.2 The Spleen; 2.1.2.3 The Bones; 2.1.2.4 The Lungs; 2.1.2.5 The Liver; 2.1.3 Dendritic Cells; 2.1.4 Neutrophils; 2.1.4.1 Migration From the Circulation; 2.1.4.2 Neutrophil-Driven Bacterial Killing; 2.1.5 Eosinophils; 2.1.6 Mast Cells and Basophils; 2.1.7 Innate Lymphoid Cells; 2.1.7.1 Natural Killer Cells.
- 2.2.4.2 Dectin-2 and Mincle2.2.4.3 Tyrosine-Based Activation Motif-Independent Signaling by C-Type Lectin Receptorss; 2.2.4.4 C-Type Lectin Receptors Can Act as Inhibitory Receptors; 2.2.5 Cytoplasmic Pattern Recognition Receptors; 2.2.6 Nucleotide-Binding, Leucine-Rich Repeat-Containing Receptor Signaling; 2.2.6.1 NOD1 and NOD2 Receptor Signaling; 2.2.6.2 Inflammasome-Based Signaling; 2.2.7 Nucleic Acid-Sensing Immune Receptors in the Cytoplasm; 2.2.7.1 The RIG-I Family; 2.2.7.2 The PYHIN Receptor Family; 2.2.7.3 STING and the Innate Detection of Nucleic Acids; REFERENCES AND FURTHER READING.