Bioinformatics methods in clinical research /

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Bibliographic Details
Imprint:New York, N.Y. : Humana Press, ©2010.
Description:1 online resource (x, 387 pages) : illustrations (some color)
Language:English
Series:Springer Protocols
Methods in molecular biology, 1940-6029 ; 593
Springer protocols (Series)
Methods in molecular biology (Clifton, N.J.) ; v. 593.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11281168
Hidden Bibliographic Details
Other authors / contributors:Matthiesen, Rune.
ISBN:9781603271943
1603271945
9781603271936
1603271937
Digital file characteristics:text file
PDF
Notes:Includes bibliographical references and index.
Restrictions unspecified
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212
English.
digitized 2010 HathiTrust Digital Library committed to preserve
Print version record.
Summary:Integrated bioinformatics solutions have become increasingly valuable in past years, as technological advances have allowed researchers to consider the potential of omics for clinical diagnosis, prognosis, and therapeutic purposes, and as the costs of such techniques have begun to lessen. In Bioinformatics Methods in Clinical Research, experts examine the latest developments impacting clinical omics, and describe in great detail the algorithms that are currently used in publicly available software tools. Chapters discuss statistics, algorithms, automated methods of data retrieval, and experimental consideration in genomics, transcriptomics, proteomics, and metabolomics. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, provides practical examples illustrating methods, results, and conclusions from data mining strategies wherever possible, and includes a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Informative and ground-breaking, Bioinformatics Methods in Clinical Research establishes a much-needed bridge between theory and practice, making it an indispensable resource for bioinformatics researchers.
Other form:Print version: Bioinformatics methods in clinical research. New York, NY : Humana ; London : Springer [distributor], ©2010 9781603271936
Standard no.:10.1007/978-1-60327-194-3

MARC

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505 0 |a Introduction to omics / Ewa Gubb and Rune Matthiesen -- Machine learning : an indispensable tool in bioinformatics / Iñaki Inza [and others] -- SNP-PHAGE : high-throughput SNP discovery pipeline / Ana M. Aransay, Rune Matthiesen, and Manuela M. Regueiro -- R classes and methods for SNP array data / Robert B. Scharpf and Ingo Ruczinski -- Overview on techniques in cluster analysis / Itziar Frades and Rune Matthiesen -- Nonalcoholic steatohepatitis, animal models, and biomarkers : what is new? : / Usue Ariz [and others] -- Biomarkers in breast cancer / María dM. Vivanco -- Genome-wide proximal promoter analysis and interpretation / Elizabeth Guruceaga [and others] -- Proteomics facing the combinatorial problem / Rune Matthiesen and António Amorim -- Methods and algorithms for relative quantitative proteomics by mass spectrometry / Rune Matthiesen and Ana Sofia Carvalho -- Feature selection and machine learning with mass spectrometry data / Susmita Datta and Vasyl Pihur -- Computational methods for analysis of two-dimensional gels / Gorka Lasso and Rune Matthiesen -- Mass spectrometry in epigenetic research / Hans Christian Beck -- Computational approaches to metabolomics / David S. Wishart -- Algorithms and methods for correlating experimental results with annotation databases / Michael Hackenberg and Rune Matthiesen -- Analysis of biological processes and diseases using text mining approaches / Martin Krallinger, Florian Leitner, and Alfonso Valencia. 
588 0 |a Print version record. 
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