Drug delivery to the central nervous system /

Saved in:

Bibliographic Details
Imprint:	New York, N.Y. : Humana Press, ©2010.
Description:	1 online resource (xii, 321 pages) : illustrations (some color)
Language:	English
Series:	Springer protocols Neuromethods, 1940-6045 ; 45 Springer protocols (Series) Neuromethods ; 45.
Subject:	Drug delivery systems. Central nervous system -- Diseases -- Chemotherapy. Drug Delivery Systems -- methods. Central Nervous System Diseases -- drug therapy. Central nervous system -- Diseases -- Chemotherapy. Drug delivery systems.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11282419

Hidden Bibliographic Details
Other authors / contributors:	Jain, K. K. (Kewal K.)
ISBN:	9781607615293 1607615290 9781607615286 1607615282
Digital file characteristics:	text file
Notes:	Includes bibliographical references and index. English. Print version record.
Summary:	Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain.
Other form:	Print version: Drug delivery to the central nervous system. New York, N.Y. : Humana Press, 2010 9781607615286
Standard no.:	10.1007/978-1-60761-529-3

Table of Contents:

An overview of drug delivery to the CNS / K.K. Jain
Receptor-mediated transport of drugs across the BBB / J.-M. Feng, P.C.W. Lui and J.Y. Li
Disruption of blood-brain barrier by focused ultrasound for targeted drug delivery to the brain / N. Vykhodtseva
Prediction of blood-brain barrier penetration by drugs / K. Lanevskij [and others]
Intraparenchymal delivery and its discontents / R. Raghavan
Intrathecal drug delivery by implanted pumps / S. Belverud, A. Mogilner and M. Schulder
Intracarotid drug delivery: Revisiting the past or looking into the future / S. Joshi
Vesicular systems for intranasal drug delivery / I.A. Alsarra [and others]
Convection-enhanced drug delivery and monitoring in a rat model / Y. Mardor and Z. Ram
Intrathecal delivery of stem cells to the spinal cord / B. Neuhuber and I. Fischer
CNS delivery of peptides across the BBB using the dual-artery in situ brain perfusion model / K.A. Witt [and others]
An engineered peptide compound platform technology incorporating angiopep for crossing the BBB / R. Gabathuler
Adeno-associated virus mediated gene therapy in ischemic stroke / Y. Wang, F. Yuan and G.-Y. Yang
Use of mesenchymal stem cells for gene delivery to intracranial glioma / S.-S. Jeun [and others]
Convection-enhanced drug delivery to the brain / D. Ding [and others].

Similar Items