Stem cells and myocardial regeneration /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, ©2007.
Description:1 online resource (xiii, 315 pages) : illustrations (some color)
Language:English
Series:Contemporary cardiology
Contemporary cardiology (Totowa, N.J.)
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11283258
Hidden Bibliographic Details
Other authors / contributors:Penn, Marc S.
ISBN:1588296644
9781588296641
9781597452724
1597452726
Digital file characteristics:text file PDF
Notes:Includes bibliographical references and index.
Summary:Over the past 5 years there has been great excitement and controversy in the scientific, financial, and lay literature for the potential of stem cell-based strategies for the prev- tion and treatment of chronic heart failure (CHF). Not that long ago we believed we were born with a set number of cardiac myocytes and that once damaged there was no hope to replace them. The interest in the field stems from the magnitude of cardiovascular disease in the world. Our ability to treat and help patients survive acute myocardial infarction (MI) has resulted in a near epidemic of CHF. There are more than 5 million Americans who currently carry the diagnosis of CHF. With more than 1 million MIs a year in the United States, there are approx 500,000 new cases of CHF diagnosed each year. The goal of Stem Cells and Myocardial Regeneration is to present, in a coherent manner, the current state of knowledge of stem cell-based therapies for cardiac dysfunction, including current findings in both the laboratory and the clinic trials. The first section of this Stem Cells and Myocardial Regeneration focuses on the magnitude of the problem and the successes and failures of what we consider optimal medical therapy. It is on this background that stem cell-based therapy needs to build.
Other form:Print version: Stem cells and myocardial regeneration. Totowa, N.J. : Humana Press, ©2007 1588296644 9781588296641
Standard no.:9786610832781
2425965

MARC

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245 0 0 |a Stem cells and myocardial regeneration /  |c edited by Marc S. Penn. 
260 |a Totowa, N.J. :  |b Humana Press,  |c ©2007. 
300 |a 1 online resource (xiii, 315 pages) :  |b illustrations (some color) 
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490 1 |a Contemporary cardiology 
504 |a Includes bibliographical references and index. 
505 0 |a The challenge for stem cell therapy: overview of the problem: heart attack and heart failure -- Hematopoietic stem cells for myocardial regeneration -- Mesenchymal stem cells for cardiac therapy -- Multipotent adult progenitor cells -- Mesenchymal progenitor cells for vascular formation and cardiac muscle regeneration -- Umbilical cord blood stem cells for myocardial regeneration and angiogenesis -- Endogenous cardiac stem cells -- Embryonic stem cells for myocardial repair -- Chemokin and homing factor expression in acute myocardial infarction and chronic heart failure -- Stem cell differentiation toward a cardiac myocyte phenotype -- Electrical coupling and/or ventricular tachycardia risk of cell therapy -- Cell therapy for myocardial damage: arrhythmia risk and mechanisms -- Aspects of percutaneous cellular cardiomyoplasty -- Stem cells and myocardial regeneration: open-chest/minimally invasive surgical techniques -- Measures of effective cell based therapies -- Whole bone marrow transplantation -- Clinical angioblast therapy -- Use of skeletal myoblasts for the treatment of chronic heart failure -- Bone marrow and angioblast transplantation -- Strategies for cytokine modification and stem cell mobilization for acute myocardial infarction -- 21 summary and future challenges. 
520 |a Over the past 5 years there has been great excitement and controversy in the scientific, financial, and lay literature for the potential of stem cell-based strategies for the prev- tion and treatment of chronic heart failure (CHF). Not that long ago we believed we were born with a set number of cardiac myocytes and that once damaged there was no hope to replace them. The interest in the field stems from the magnitude of cardiovascular disease in the world. Our ability to treat and help patients survive acute myocardial infarction (MI) has resulted in a near epidemic of CHF. There are more than 5 million Americans who currently carry the diagnosis of CHF. With more than 1 million MIs a year in the United States, there are approx 500,000 new cases of CHF diagnosed each year. The goal of Stem Cells and Myocardial Regeneration is to present, in a coherent manner, the current state of knowledge of stem cell-based therapies for cardiac dysfunction, including current findings in both the laboratory and the clinic trials. The first section of this Stem Cells and Myocardial Regeneration focuses on the magnitude of the problem and the successes and failures of what we consider optimal medical therapy. It is on this background that stem cell-based therapy needs to build. 
650 0 |a Stem cells  |x Therapeutic use. 
650 0 |a Regeneration (Biology)  |0 http://id.loc.gov/authorities/subjects/sh85112343 
650 0 |a Myocardium  |x Regeneration.  |0 http://id.loc.gov/authorities/subjects/sh85059696 
650 0 |a Transplantation of organs, tissues, etc.  |0 http://id.loc.gov/authorities/subjects/sh85137008 
650 1 2 |a Myocardium  |x cytology 
650 1 2 |a Stem Cells  |x physiology 
650 2 2 |a Regeneration  |x physiology 
650 2 |a Regeneration  |0 https://id.nlm.nih.gov/mesh/D012038 
650 2 |a Transplantation  |0 https://id.nlm.nih.gov/mesh/D014180 
650 2 |a Organ Transplantation  |0 https://id.nlm.nih.gov/mesh/D016377 
650 2 |a Tissue Transplantation  |0 https://id.nlm.nih.gov/mesh/D016378 
650 6 |a Cellules souches  |x Emploi en thérapeutique. 
650 6 |a Régénération (Biologie) 
650 6 |a Myocarde  |x Régénération. 
650 6 |a Greffe (Chirurgie) 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Heart.  |2 bisacsh 
650 7 |a MEDICAL  |x Cardiology.  |2 bisacsh 
650 0 7 |a Myocardium  |x Regeneration.  |2 cct 
650 0 7 |a Transplantation of organs, tissues, etc.  |2 cct 
650 0 7 |a Myocardium  |x cytology.  |2 cct 
650 0 7 |a Stem Cells  |x physiology.  |2 cct 
650 0 7 |a Regeneration  |x physiology.  |2 cct 
650 0 7 |a Stem cells  |x Therapeutic use.  |2 cct 
650 0 7 |a Regeneration (Biology)  |2 cct 
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650 7 |a Regeneration (Biology)  |2 fast  |0 (OCoLC)fst01093042 
650 7 |a Transplantation of organs, tissues, etc.  |2 fast  |0 (OCoLC)fst01154919 
700 1 |a Penn, Marc S.  |0 http://id.loc.gov/authorities/names/n2006180703 
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