Cellular signaling and innate immune responses to RNA virus infections /

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Bibliographic Details
Imprint:	Washington, D.C. : ASM Press, ©2009.
Description:	1 online resource (xiii, 436 pages) : illustrations (some color)
Language:	English
Subject:	RNA viruses. Natural immunity. Cellular signal transduction. Virus diseases -- Immunological aspects. RNA Viruses -- immunology. Immunity, Innate -- immunology. Signal Transduction -- immunology. Cellular signal transduction. Natural immunity. RNA viruses. Virus diseases -- Immunological aspects.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11300001

Hidden Bibliographic Details
Other authors / contributors:	Brasier, Allan R., editor. García-Sastre, Adolfo, editor. Lemon, Stanley M., editor.
ISBN:	9781683671411 1683671414 9781555815561 1555815561 1555814360 9781555814366 1283033860 9781283033862 9786613033864 6613033863 9781555814366
Digital file characteristics:	data file
Notes:	Includes bibliographical references and index. English. Print version record.
Summary:	Divided into two major sections, this volume synthesizes recent findings in this fast-moving field while also reviewing accepted knowledge. The first part focuses on the antiviral signaling pathways in the host, including specific pattern recognition receptors (PRRs) and how these cellular alarms signal the innate immune response. The second section examines the ways in which specific major RNA virus families interact with, activate, and elude these signaling pathways and responses.
Other form:	Print version: Cellular signaling and innate immune responses to RNA virus infections. Washington, D.C. : ASM Press, ©2009 9781555814366

Table of Contents:

Role of toll-like receptors in the innate immune response to RNA viruses / Sinéad E. Keating and Andrew G. Bowie
Cytoplasmic pattern receptors and signaling in viral infections / Osamu Takeuchi and Shizuo Akira
Mitochondrial antiviral signaling / Vijay G. Bhoj and Zhijian J. Chen
Interferon regulatory factors and the atypical IKK-related kinases TBK1 and IKK? : essential players in the innate immune response to RNA virus infection / Meztli Arguello, Suzanne Paz, and John Hiscott
Jak-stat pathway in response to virus infection / Joan E. Durbin
Interferons and antiviral action / Christine L. White and Ganes C. Sen
The nuclear factor-kB transcription factor pathway / Amer A. Beg and Xingyu Wang
The nuclear factor-kB signaling network : insights from systems approaches / Allan R. Brasier
Type 1 interferon signaling in shaping cellular innate and adaptive immunity to viral infection / Christine A. Biron
Biological impact of type I interferon induction pathways beyond their antivirus activity / Bahram Razani [and others]
Human genetic factors involved in viral pathogenesis / Lennart Svensson and Elin Kindberg
RNA virus families : distinguishing characteristics, differences, and similarities / Peter W. Mason and Frank Scholle.
Rhabdoviruses and mechanisms of type I interferon antagonism / Krzysztof Brzózka and Karl-Klaus Conzelmann
Filoviruses / Christopher F. Basler
Inhibition of antiviral signaling pathways by paramyxovirus proteins / Antonella Casola [and others]
Suppression of innate immunity by orthomyxoviruses / Randy A. Albrecht and Adolfo García-Sastre
Bunyaviruses and innate immunity / Friedemann Weber and Richard M. Elliott
Arenaviruses / Juan C. de la Torre
Regulation of innate immunity by the flaviviridae / Brenda L. Fredericksen and Michael Gale Jr.
Evasion of innate host antiviral defenses by picornaviruses / Stanley M. Lemon
Togaviruses / William B. Klimstra and Kate D. Ryman
Coronaviruses and arteriviruses / Krishna Narayanan and Shinji Makino
Caliciviridae and astroviridae / Susana Guix and Mary K. Estes
Innate immune responses elicited by reovirus and rotavirus / Barbara Sherry, John T. Patton, and Terence S. Dermody
Summary and perspectives / Allan R. Brasier, Adolfo García-Sastre, and Stanley M. Lemon.

Cellular signaling and innate immune responses to RNA virus infections /

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