Life's vital link : the astonishing role of the placenta /

This fine book brings attention to an often-overlooked and discarded body organ, the placenta--a complicated gateway for the active passage of oxygen and nutrients and elimination of wastes. Retired reproductive immunologist Loke (emer., Univ. of Cambridge, UK) shares his expertise as a researcher in embryology, endocrinology, genetics, and biochemical cellular physiology. He also incorporates information on evolutionary developments, compares plant and animal reproduction and various placental types, and discusses cultural values related to the placenta throughout the world. He describes the ingenious battles and balances between the changing systems of the mother and the growing semiforeign fetus (half of the genetic code is from the father). Difficult terms (e.g., "syncytiotrophoblast") are defined, acronyms are spelled out, and the author reviews and summarizes. However, aside from the first and last chapters, this work is still too advanced for general readers or lower-level undergraduates. Popular and/or controversial topics briefly discussed include surrogacy, DES (diethylstilbestrol), preeclampsia, pregnancy and prenatal testing, donating and freezing eggs, stem cell therapies, in vitro fertilization, organ transplants, and use of placenta extracts in cosmetics. Very helpful illustrative figures, a glossary, and chapter endnotes support the text. Valuable for upper-level biology majors as supplementary reading. Summing Up: Highly recommended. Upper-division undergraduates and above. E. R. Paterson emeritus, SUNY College at Cortland

Despite being one of the body's most short-lived organs-arising at conception and dying at the birth of the baby-the placenta deserves to be considered among the most complex and important parts of the human body, argues Loke (Human Implantation, co-author) in this surprisingly delightful book. During its lifetime, the placenta fills many roles: it anchors the developing fetus in the womb; serves as its lungs, kidneys, and digestive tract; transfers waste products from the uterus to the mother; and produces hormones that manipulate maternal behavior in a way that benefits the fetus. Loke, an emeritus professor of reproductive immunology at the University of Cambridge, argues that the placenta has much more to offer in addition to these fascinating functions. Understanding placental growth patterns may shed light on the etiology of cancer; it could also help doctors combat the problem of tissue rejection in organ transplant patients. The placenta is even powerful enough to overcome the effects of time, in a way-post-menopausal women can bring a previously fertilized egg to term thanks to the placenta's ability to control endocrine levels. Accessible enough for a general readership, Loke's work provides the key to a truly unique world. 20 b&w illus. & glossary. (Aug.) (c) Copyright PWxyz, LLC. All rights reserved.