Frontiers in clinical drug research. Volume 3, Diabetes and obesity /
Saved in:
| Imprint: | Sharjah : Bentham Science Publishers, 2016. |
|---|---|
| Description: | 1 online resource (257 pages) |
| Language: | English |
| Series: | Frontiers in Clinical Drug Research - Diabetes and Obesity Frontiers in Clinical Drug Research - Diabetes and Obesity. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11307256 |
MARC
| LEADER | 00000cam a2200000Mi 4500 | ||
|---|---|---|---|
| 001 | 11307256 | ||
| 006 | m o d | ||
| 007 | cr |n|---||||| | ||
| 008 | 161224s2016 xx o 000 0 eng d | ||
| 005 | 20240510213418.2 | ||
| 019 | |a 1011009773 | ||
| 020 | |a 9781681082479 |q (electronic bk.) | ||
| 020 | |a 1681082470 |q (electronic bk.) | ||
| 035 | |a (OCoLC)966464117 |z (OCoLC)1011009773 | ||
| 035 | 9 | |a (OCLCCM-CC)966464117 | |
| 040 | |a EBLCP |b eng |e pn |c EBLCP |d OCLCQ |d N$T |d OCLCF |d AGLDB |d D6H |d OCLCQ |d VTS |d STF |d OCLCQ |d AJS | ||
| 049 | |a MAIN | ||
| 050 | 4 | |a RC660 |b .F76 2016eb | |
| 072 | 7 | |a HEA |x 039000 |2 bisacsh | |
| 072 | 7 | |a MED |x 014000 |2 bisacsh | |
| 072 | 7 | |a MED |x 022000 |2 bisacsh | |
| 072 | 7 | |a MED |x 112000 |2 bisacsh | |
| 072 | 7 | |a MED |x 045000 |2 bisacsh | |
| 245 | 0 | 0 | |a Frontiers in clinical drug research. |n Volume 3, |p Diabetes and obesity / |c editor, Atta-ur-Rahman. |
| 260 | |a Sharjah : |b Bentham Science Publishers, |c 2016. | ||
| 300 | |a 1 online resource (257 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Frontiers in Clinical Drug Research - Diabetes and Obesity | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a PREFACE ; List of Contributors ; Exendin-4 and Its Derivatives for Diabetes and Obesity: Old Story and New Hope ; INTRODUCTION; The Discovery of Exendin-4; Fundamental Aspects of Exendin-4; Present Status of Exendin-4 for the Treatment of Type 2 Diabetes; INTERACTION OF EXENDIN-4 WITH GLP-1 RECEPTOR; GLP-1 Receptor and Its Dimerization; Exendin-4 Binding to GLP-1 Receptor; MODIFICATION OF EXENDIN-4 AND RELATED APPLICATIONS; Improved Stability and Binding Affinity; Improved Oral Bioavailability; Vitamin Conjugation; Low Molecular Weight Chitosan Conjugation. | |
| 505 | 8 | |a Cholera Toxin B Subunit FusionExtended Half-life and Long Acting Preparations; Dimeric Exendin-4; Bile Acid Conjugation; Poly (Ethylene Glycol) Conjugation; Human Serum Albumin Conjugation; Albumin-Binding Domain Conjugation; Hyaluronate Conjugation; Mixed Strategies; CONCLUSION AND FUTURE PERSPECTIVES; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; The Growth Hormone/Insulin-like Growth Factor System in the Management of Diabetes and Obesity ; INTRODUCTION; Overview of the GH/IGF System; Metabolic Actions of the GH/IGF System ; THERAPEUTIC CONSIDERATIONS; Obesity. | |
| 505 | 8 | |a Severe Insulin ResistanceType 2 Diabetes; Type 1 Diabetes; CONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Insulin, Cardiovascular Function and Long-Term Diabetic Complications ; INTRODUCTION; The Role of Hyperglycemia; Insulin and Muscle Capillary Function; Muscle Sympathetic Nerve Activity; Insulin and Capillary Recruitment; NO, Nitric Oxide, Endothelium-derived Relaxing Factor; Insulin, Skeletal Muscle Blood Flow and Obesity; Kidney: Insulin and Albumin Excretion; Kidney: Albumin Excretion and Diabetic Nephropathy; Long-term Diabetic Complications; Drug Discovery Science. | |
| 505 | 8 | |a CONCLUSIONCONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Pharmacological Relevance of Novel Biomarkers Associated with Diabetes-mellitus Related Infertility ; 1. INTRODUCTION; 2. TESTICULAR PHYSIOLOGY AND ANATOMY; 2.1. Sertoli Cells: Morphology and Structure; 2.2. Spermatogenesis: A Brief Overview; 2.3. Regulation of Spermatogenesis; 2.3.1. Hormonal Control of Spermatogenesis; 3. TESTICULAR METABOLIC CO-OPERATION; 3.1. The Metabolism of Sertoli Cells; 3.2. The Metabolic Support of Developing Germ Cells. | |
| 505 | 8 | |a 3.3. The Metabolic Requirements of Spermatozoa: Considerations about Glucose Metabolism4. IMPACT OF DIABETIC STAGES IN MALE FERTILITY; 4.1. Glycemic Trajectories: From the High-risk State to the Established Diabetes Mellitus; 4.2. The Effects of Diabetes Mellitus in Male Fertility: A Clinical Perspective; 5. DIABETES MELLITUS AS A THREAT FOR TESTICULAR METABOLISM; 5.1. Testicular Oxidative Stress Induced by Progressive Diabetic Stages; 6. TESTICULAR METABOLIC CO-OPERATION AS POTENTIAL PHARMACOLOGIC TARGET TO COUNTERACT DIABETES MELLITUS -- ASSOCIATED SUBFERTILITY AND INFERTILITY. | |
| 500 | |a 7. INSIGHTS IN THE EPIGENETIC OUTCOMES OF DIABETES MELLITUS ON MALE FERTILITY. | ||
| 650 | 0 | |a Diabetes. |0 http://id.loc.gov/authorities/subjects/sh85037456 | |
| 650 | 0 | |a Diabetes |x Treatment. | |
| 650 | 0 | |a Obesity. |0 http://id.loc.gov/authorities/subjects/sh85093646 | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x General. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Diseases. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Evidence-Based Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Internal Medicine. |2 bisacsh | |
| 650 | 7 | |a Diabetes. |2 fast |0 (OCoLC)fst00892147 | |
| 650 | 7 | |a Diabetes |x Treatment. |2 fast |0 (OCoLC)fst00892199 | |
| 650 | 7 | |a Obesity. |2 fast |0 (OCoLC)fst01042738 | |
| 655 | 0 | |a Electronic books. | |
| 655 | 4 | |a Electronic books. | |
| 700 | 1 | |a Atta-ur-Rahman. | |
| 776 | 0 | 8 | |i Print version: |a Atta-ur-Rahman. |t Frontiers in Clinical Drug Research - Diabetes and Obesity volume 3. |d Sharjah : Bentham Science Publishers, ©2016 |z 9781681082486 |
| 830 | 0 | |a Frontiers in Clinical Drug Research - Diabetes and Obesity. | |
| 903 | |a HeVa | ||
| 929 | |a oclccm | ||
| 999 | f | f | |i 82b7251f-4653-554c-b4d3-7de8f521cc26 |s 3c99a130-b636-5d5d-8492-c793d2af346f |
| 928 | |t Library of Congress classification |a RC660 .F76 2016eb |l Online |c UC-FullText |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=e000xna&AN=1511900 |z eBooks on EBSCOhost |g ebooks |i 12447195 | ||