Public health risk assessment for human exposure to chemicals /
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| Author / Creator: | Asante-Duah, D. Kofi, author. |
|---|---|
| Edition: | Second edition. |
| Imprint: | Dordrecht, Netherlands : Springer, [2017] |
| Description: | 1 online resource (xxi, 600 pages) : illustrations (some color) |
| Language: | English |
| Series: | Environmental pollution, 1566-0745 ; volume 27 Environmental pollution (Dordrecht, Netherlands) ; v. 27. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11308365 |
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| 100 | 1 | |a Asante-Duah, D. Kofi, |e author. | |
| 245 | 1 | 0 | |a Public health risk assessment for human exposure to chemicals / |c Kofi Asante-Duah. |
| 250 | |a Second edition. | ||
| 264 | 1 | |a Dordrecht, Netherlands : |b Springer, |c [2017] | |
| 300 | |a 1 online resource (xxi, 600 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Environmental pollution, |x 1566-0745 ; |v volume 27 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed July 11, 2017). | |
| 588 | 0 | |a Online resource; title from PDF title page (SpringerLink, viewed June 28, 2017). | |
| 505 | 0 | |a Preface; Acknowledgements; Contents; Part I: Problem Diagnosis: A General Overview of the Origins and Nature of Chemical Exposure Problems; Chapter 1: Introduction; 1.1 Chemical Origins: Coming to Terms with the Several Chemicals in Modern Society; 1.1.1 The Wide-Ranging Scope of Chemical Hazard Problems: A General Overview; 1.1.2 The Wide-Ranging Scope of Chemical Hazard Problems: Lead Exposures as an Example; 1.2 Public Health and Socio-Economic Implications of Chemical Exposure Problems; 1.2.1 The General Nature of Human Health Effects From Chemical Exposures. | |
| 505 | 8 | |a 1.3 Strategically Managing the Chemical Exposure Problem: The Need for Public Health Risk AssessmentChapter 2: Anatomical and Physiological Perspectives on Human Exposure to Chemicals; 2.1 An Overview of Human Contact Sites and Target Organs Most Susceptible to Chemical Exposures; 2.1.1 Fundamentals of Human Physiology; 2.1.2 Target Organ Toxicity; 2.2 The General Nature of Chemical Hazards and Human Response from Exposure to Chemical Substances; 2.2.1 Classification of Chemical Toxicity; 2.2.2 Factors Influencing Chemical Toxicity to Humans and Human Response to Chemical Toxicants. | |
| 505 | 8 | |a Box 2.1 Factors Potentially Influencing Human Response to Toxic Chemicals2.2.2.1 Distribution and Storage of Toxicants in the Human Body; 2.2.2.2 Toxicokinetics/Pharmacokinetics vs. Toxicodynamics/Pharmacodynamics; 2.3 The Pharmacokinetics and Pharmacodynamics of Chemicals in Human Exposure Environments; 2.3.1 Elements of Toxicokinetics/Pharmacokinetics; 2.3.2 Physiologically-Based Pharmacokinetic (PBPK) Modeling; 2.3.3 Characterization of Physiologically-Based Pharmacokinetic (PBPK) Models; 2.3.3.1 PBPK Model Structure and Mechanics/Descriptors. | |
| 505 | 8 | |a 2.3.3.2 Documenting PBPK Modeling Outcomes/Results2.3.4 Application/Use of Mechanistic Data and Physiologically-Based Pharmacokinetic (PBPK) Models in Risk Assessments; 2.3.5 Post-PBPK Modeling and Dosimetry Adjustments: The Pragmatic Role of Tissue/Target Organ Dosimetry in Risk Assessments; Chapter 3: Archetypical Chemical Exposure Problems; 3.1 Formulation of Archetypical Chemical Exposure Problems; 3.1.1 The Case for Human Exposures to Airborne Chemical Toxicants; 3.1.1.1 Indoor Air Quality Problems: General Sources of Indoor Volatile [Organic] Chemicals. | |
| 505 | 8 | |a 3.1.1.2 Chemical Vapor Intrusion into Buildings3.1.2 Water Pollution Problems and Human Exposures to Chemicals in Water as an Example; 3.1.3 Contaminated Soil Problems and Human Exposures to Chemicals on Land; 3.1.4 Human Exposures to Chemicals in Foods and Household/Consumer Products; 3.2 Quantification Process for the General Types of Human Exposures to Chemical Toxicants; Part II: A Public Health Risk Assessment Taxonomy: Nomenclatural Components, Concepts, Principles, and Evaluation Strategies; Chapter 4: Principles and Concepts in Risk Assessment. | |
| 520 | |a This book provides a concise, yet comprehensive overview of the many facets relating to human health risk assessments in relation to chemical exposure problems. It presents some very important tools and methodologies that can be used to address chemical exposure and public health risk management problems in a consistent, efficient, and cost-effective manner. On the whole, the book represents a collection and synthesis of the principal elements of the risk assessment process that may be used to more effectively address issues pertaining to human exposures to chemicals found in modern societies. This also includes an elaboration of pertinent risk assessment concepts and techniques/methodologies for performing human health risk assessments. Written for both the novice and the experienced, the subject matter of this book is an attempt at offering a simplified and systematic presentation of public health risk assessment methods and application tools? all these facilitated by a layout that will carefully navigate the user through the major processes involved. A number of illustrative example problems are interspersed throughout the book, in order to help present the book in an easy-to-follow, pragmatic manner. | ||
| 650 | 0 | |a Health risk assessment. |0 http://id.loc.gov/authorities/subjects/sh85059598 | |
| 650 | 0 | |a Environmental toxicology. |0 http://id.loc.gov/authorities/subjects/sh96003462 | |
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| 650 | 7 | |a Environmental toxicology. |2 fast |0 (OCoLC)fst00913536 | |
| 650 | 7 | |a Health risk assessment. |2 fast |0 (OCoLC)fst00953250 | |
| 655 | 4 | |a Electronic books. | |
| 773 | 0 | |t Springer eBooks | |
| 776 | 0 | 8 | |i Print version: |a Asante-Duah, D. Kofi. |t Public health risk assessment for human exposure to chemicals. |b Second edition. |d Dordrecht, Netherlands : Springer, [2017] |z 9402410376 |z 9789402410372 |w (OCoLC)964379612 |
| 830 | 0 | |a Environmental pollution (Dordrecht, Netherlands) ; |v v. 27. | |
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| 928 | |t Library of Congress classification |a RA566.27 |l Online |c UC-FullText |u https://link.springer.com/10.1007/978-94-024-1039-6 |z Springer Nature |g ebooks |i 12546933 | ||