Organelle contact sites : from molecular mechanism to disease /

Organelle contact sites : from molecular mechanism to disease /

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Bibliographic Details
Imprint:Singapore : Springer, [2017]
©2017
Description:1 online resource (viii, 257 pages) : color illustrations
Language:English
Series:Advances in experimental medicine and biology, 2214-8019 ; volume 997
Advances in experimental medicine and biology ; v. 997.
Subject:
Cell membranes -- Metabolism.
Endoplasmic reticulum -- Metabolism.
Mitochondrial membranes -- Metabolism.
Cell interaction.
Humans.
Organelles.
Mitochondrial Membranes.
Cell interaction.
Electronic book.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11350183
Hidden Bibliographic Details
Other authors / contributors:Tagaya, Mitsuo, 1958- editor.
Simmen, Thomas, editor.
ISBN:9789811045677
9811045674
9789811045660
9811045666
Digital file characteristics:text file PDF
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (EBSCO, viewed August 29, 2017).
Summary:"This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders, and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases. Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come. This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction. Additionally, it will stimulate graduate students and postdocs who will energize, drive, and develop the research field in the near future"--Publisher's description.
Other form:Printed edition: 9789811045660
Standard no.:10.1007/978-981-10-4567-7
Table of Contents:
  • Organelle communication at membrane contact sites (MCS): from curiosity to center stage in cell biology and biomedical research / Thomas Simmen, Mitsuo Tagaya
  • Over six decades of discovery and characterization of the architecture at mitochondria-associated membranes (MAMS) / Maria Sol Herrera-Cruz, Thomas Simmen
  • Regulation of mitochondrial dynamics and autophagy by the mitochondria-associated membrane / Mitsuo Tagaya, Kohei Arasaki
  • Endoplasmic reticulum-mitochondria communication through Ca2+ signaling: the importance of mitochondria-associated membranes (MAMS) / Saverio Marchi, Mart Bittremieux, Sonia Missiroli, Claudia Morganti, Simone Patergnani [and others]
  • Ceramide transport from the endoplasmic reticulum to the trans Golgi region at organelle membrane contact sites / Kentaro Hanada
  • Endoplasmic reticulum-plasma membrane crosstalk mediated by the extended synaptotagmins / Yasunori Saheki
  • Endoplasmic reticulum-plasma membrane contacts regulate cellular excitability / Eamonn J. Dickson
  • The lipid droplet and the endoplasmic reticulum / Yuki Ohsaki, Kamil Sołtysik, Toyoshi Fujimoto
  • Role of intra- and inter-mitochondrial membrane contact sites in yeast phospholipid biogenesis / Yasushi Tamura, Toshiya Endo
  • Discovery and roles of ER-endolysosomal contact sites in disease / William Mike Henne
  • Alzheimer disease / Estela Area-Gomez, Eric A. Schon
  • Mitochondrial-associated membranes in Parkinson's disease / Nobutaka Hattori, Taku Arano, Taku Hatano, Akio Mori, Yuzuru Imai
  • Role of endoplasmic reticulum-mitochondria communication in type 2 diabetes / Jennifer Rieusset
  • Mitochondrial-endoplasmic reticulum contact sites mediate innate immune responses / Takuma Misawa, Michihiro Takahama, Tatsuya Saitoh
  • Hepatitis C virus replication / Tetsuro Suzuki
  • Hijacking of membrane contact sites by intracellular bacterial pathogens / Isabelle Derré
  • Alterations in Ca2+ signalling via ER-mitochondria contact site remodelling in cancer / Martijn Kerkhofs, Carlotta Giorgi, Saverio Marchi, Bruno Seitaj, Jan B. Parys [and others].

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