The natural anti-gal antibody as foe turned friend in medicine /

Saved in:

Bibliographic Details
Author / Creator:	Galili, Uri, author.
Imprint:	London, United Kingdom : Academic Press, an imprint of Elsevier, [2018] ©2018
Description:	1 online resource (xviii, 300 pages) : illustrations
Language:	English
Subject:	Antigens. Antigen-antibody reactions. Antigen-antibody reactions. Antigens. Antigen-Antibody Reactions. Antigens.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11350308

Hidden Bibliographic Details
ISBN:	9780128133637 0128133635 9780128133620 0128133627
Notes:	Includes bibliographical references and index. Print version record. Online resource; title from PDF title page (EBSCO, viewed September 25, 2017).
Summary:	The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the?-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book.
Target Audience:	Specialized.
Other form:	Print version: Galili, Uri. Natural anti-gal antibody as foe turned friend in medicine. London, United Kingdom : Academic Press, an imprint of Elsevier, [2018] 0128133627 9780128133620

Table of Contents:

Anti-gal in humans and its antigen the ?-gal epitope
Why do we produce anti-gal
Anti-gal comprises most of anti-blood group b antibodies
Anti-gal interaction with Trypansoma, Leishmania, and Plasmodium parasites
Anti-gal b cells are tolerized by a ?-gal epitopes in the absence of t cell help
Anti-gal and other immune barriers in xenotransplantation
Anti-gal IgE mediates allergies to red meat
Anti-gal and autoimmunity
Anti-gal-mediated amplification of viral vaccine efficacy
Cancer immunotherapy by anti-gal-mediated in situ conversion of tumors into autologous vaccines
Anti-gal as cancer cell destroying antibody and as antibiotics targeted by ?-gal bifunctional molecules
Acceleration of wound and burn healing by anti-gal/?-gal nanoparticles interaction
Anti-gal and anti-non gal antibodies in regeneration of extracellular matrix bio-implants
Post infarction regeneration of ischemic myocardium by intramyocardial injection of ?-gal nanoparticles
Regeneration of injured spinal cord and peripheral nerves by ?-gal nanoparticles
Inhalation of ?-gal/sialic acid liposomes for decreasing influenza virus infection.

Similar Items